CYCLOPHILIN A

CYCLOPHILIN A
  • CAS No.:95076-93-0
Other grades of this product :
CYCLOPHILIN A Basic information
Product Name:CYCLOPHILIN A
Synonyms:EC 5.2.1.8;CYCLOPHILIN;CYCLOPHILIN A;CYCLOPHILIN A (HUMAN);CYCLOPHILIN HUMAN;PEPTIDYLPROLINE CIS-TRANS-ISOMERASE;CYCLOPHILIN HUMAN, RECOMBINANTEXPRESSED IN E. COLI;CYCLOPHILIN FROM CALF THYMUS
CAS:95076-93-0
MF:
MW:0
EINECS:
Product Categories:
Mol File:Mol File
CYCLOPHILIN A Chemical Properties
storage temp. -20°C
form buffered aqueous solution
Safety Information
Safety Statements 24/25
WGK Germany -
MSDS Information
ProviderLanguage
SigmaAldrich English
CYCLOPHILIN A Usage And Synthesis
UsesCyclophilin A human has been used in the study to interpret the mechanisms by which extracellular CyPA initiates endothelial activation.
General DescriptionCyclophilins are a family of extremely conserved proteins, known as immunophilins. Cyclophilin A (CyPA) is present in all tissues in prokaryotes and eukaryotes. It is present in all organs of human. Cyclophilin A (CyPA), a 20 kDa chaperone protein, that is liberated from vascular smooth muscle cells (VSMCs).
Biochem/physiol ActionsCyclophilin A (CyPA) participates in intracellular signalling and protein trafficking. It helps to control other proteins activity. CyPA plays a physiological and pathological role in cardiovascular diseases. Hence it acts as an important biomarker and mediator in several cardiovascular diseases, like vascular stenosis, atherosclerosis and abdominal aortic aneurysms.?CyPA can induce the proliferation and inflammatory cell migration of vascular smooth muscle cells (VSMC) in vitro and in vivo.
CYCLOPHILIN A Preparation Products And Raw materials

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