7-azido-4-methylcoumarin

CAS No.：95633-27-5

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

View the full Disclaimer

Other grades of this product :

7-azido-4-methylcoumarin Basic information

Product Name:	7-azido-4-methylcoumarin
Synonyms:	7-azido-4-methylcoumarin;7-Azido-4-Methylcoumarin 97%;7-azido-4-methylchromen-2-one;Hymecromone Impurity 4
CAS:	95633-27-5
MF:	C10H7N3O2
MW:	201.18148
EINECS:
Product Categories:
Mol File:	95633-27-5.mol

7-azido-4-methylcoumarin Chemical Properties

Melting point	117.8°C
form	powder

Safety Information

MSDS Information

7-azido-4-methylcoumarin Usage And Synthesis

Uses

7-Azido-4-methylcoumarin (AzMC) is a fluorogenic probe useful for the detection of hydrogen sulfide (H₂S). The aromatic azide moiety is selectively reduced in the presence of H₂S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with λex = 365nm and λem = 450nm. The probe can be used both to monitor enzymatic production of H₂S in vitro and also to visualize H₂S in cells. The probe is highly sensitive and selective for H₂S, providing a linear detection range in vitro between 200nm – 100μM H₂S with 10μM probe, and reacting selectively with H₂S in the presence of mM concentrations of cysteine, homocysteine, glutathionine and many other common biological analytes. Caution: Use of this product with DTT, TCEP and/or biological thiols >25mM should be avoided for maximum efficiency. AzMC is readily soluble in DMSO.

7-azido-4-methylcoumarin Preparation Products And Raw materials

Welcome！

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
+86-23-6139-8061 +86-13650506873
danny@chemdad.com sales@chemdad.com
www.chemdad.com
WhatsApp +86-13650506873