Other grades of this product :
| PD168393 Basic information |
| Product Name: | PD168393 | | Synonyms: | 4-[(3-BROMOPHENYL)AMINO]-6-ACRYLAMIDOQUINAZOLINE;PD 168393;N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-propenamide;PD168393;PD-168393;PD 168393;CS-2316;N-[4-(3-Bromoanilino)quinazolin-6-yl]prop-2-enamide;PD-168393;PD 168393;2-Propenamide, N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]- | | CAS: | 194423-15-9 | | MF: | C17H13BrN4O | | MW: | 369.22 | | EINECS: | | Product Categories: | Inhibitors | | Mol File: | Mol File |
| PD168393 Chemical Properties |
| Melting point | 279℃ | | storage temp. | room temp | | solubility | insoluble in H2O; ≥1 mg/mL in EtOH with gentle warming and ultrasonic; ≥18.45 mg/mL in DMSO | | form | powder | | color | white to beige |
| PD168393 Usage And Synthesis |
| Uses | PD 168393, is an irreversible epidermal growth factor receptor (EGFR) inhibitor. | | Uses | PD168393 has been used in the acute inhibition of ErbB4. | | Definition | ChEBI: A member of the class of quinazolines carrying bromoanilino and acrylamido substituents at positions 4 and 6 respectively. | | Biochem/physiol Actions | PD168393 is a 6-acrylamido-4-anilinoquinazoline compound. It increases apoptosis in malignant peripheral nerve sheath tumor cells, stimulated by lysosomal dysfunction. |
| PD168393 Preparation Products And Raw materials |
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