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| LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT) Basic information |
| Product Name: | LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT) | | Synonyms: | LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT);LIPID A, DIPHOSPHORYL FROM SALMONELLA MINNESOTA RE-595 (R MUTANTS);LIPID A, DIPHOSPHORYL FROM SALMONELLA*MI NNESOTA RE-;lipid a, diphosphoryl from salmonella enterica serotype minnesota re 595 (re mutant);lipid A, diphosphoryl;2-deoxy-6-O-<2-deoxy-2--3-O--β-D-glucopyranosyl>-3-O--2--α-D-glucopyranose 1,4'-bis(phosphate);α-D-Glucopyranose, 2-deoxy-6-O-[2-deoxy-2-[[(3R)-1-oxo-3-[(1-oxododecyl)oxy]tetradecyl]amino]-3-O-[(3R)-1-oxo-3-[(1-oxotetradecyl)oxy]tetradecyl]-4-O-phosphono-β-D-glucopyranosyl]-2-[[(3R)-3-hydroxy-1-oxotetradecyl]amino]-, 1-(dihydrogen phosphate) 3-[(3R)-3-hydroxytetradecanoate] | | CAS: | 95991-05-2 | | MF: | C94H178N2O25P2 | | MW: | 1798.36 | | EINECS: | | Product Categories: | Complex Lipids;Glycolipids;Others | | Mol File: | 95991-05-2.mol |
| LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT) Chemical Properties |
| density | 1.13±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | 1.73±0.10(Predicted) |
| Hazard Codes | Xn | | WGK Germany | 3 |
| LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT) Usage And Synthesis |
| Uses | Lipid A, diphosphoryl from?Escherichia coli?F583 (Rd mutant) has been used:- to study the effect of various lipid A molecules on lung pericyte proliferation in vitro
- to test on THP-1 and J774A.1 cells for neopterin and nitrite formation respectively
- as lipopolysaccharides (LPS) derivatives in binding experiments
- to stimulate the spleen cells and as a mitogen stimulation for toll like receptor 4 (TLR4)
| | General Description | Lipid A is the fundamental structure of lipopolysaccharides (LPS), present in bacteria. | | Biochem/physiol Actions | Lipid A is mainly essential for the robust immunostimulatory activities of lipopolysaccharides (LPS) in human. Lipid A is the hydrophobic domain of LPS helps in anchoring LPS to the plasma membrane of bacteria. It is immunologically active and an important constituent of LPS recognised by immune system. |
| LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT) Preparation Products And Raw materials |
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