15-hexadecynoic acid

15-hexadecynoic acid
  • CAS No.:99208-90-9

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
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15-hexadecynoic acid Basic information
Product Name:15-hexadecynoic acid
Synonyms:15-hexadecynoic acid;Palmitic Acid Alkyne;hexadec-15-ynoic acid;15-HEXADECYNOIC ACID;PALMITIC ACID (15-YNE);Palmitic acid (15-yne);Alkynyl Palmitic Acid;Boc-β-homoarginine;15-hexadecyn-1-oic acid
CAS:99208-90-9
MF:C16H28O2
MW:252.39
EINECS:
Product Categories:
Mol File:99208-90-9.mol
15-hexadecynoic acid Chemical Properties
Melting point 59.1°C (estimate)
Boiling point 409.64°C (rough estimate)
density 0.9310 (rough estimate)
refractive index 1.4217 (estimate)
storage temp. -20°C
Safety Information
MSDS Information
15-hexadecynoic acid Usage And Synthesis
DescriptionAlkynyl palmitic acid can be used to identify and characterize the post-translational S-palmitoylation of proteins with Click Chemistry.
Uses15-hexadecynoic acid is a form of palmitic acid with an ω-terminal alkyne. The terminal alkyne group can be used in linking reactions, known as click chemistry; this chemistry is characterized by high dependability and specificity of the azide-alkyne bioconjugation reactions. The use of palmitic acid alkyne and related lipids in isolating palmitoylated proteins has been described.
UsesPalmitic acid (15-yne) has been used as a component of fatty acid probe stock solution for the optimization of Alk-C16 incorporation onto cellular proteins. It is also suitable for metabolic labeling.
Biochem/physiol ActionsAlkynyl palmitic acid (aPA) is a modified palmitic acid with an ω-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as ‘click chemistry′. The click chemistry reactions are rapid, convenient, versatile and regiospecific. They are easy to purify. aPA can be used for isolating palmitoylated proteins.
15-hexadecynoic acid Preparation Products And Raw materials

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