2-Pyridinethiol 1-oxide

2-Pyridinethiol 1-oxide
  • CAS No.:1121-31-9
Other grades of this product :
2-Pyridinethiol 1-oxide Basic information
Product Name:2-Pyridinethiol 1-oxide
Synonyms:MercaptypyridineNoxideanhydrous;N-Hydroxy-2-thiopyridone;pyridine-2-thiol N-oxide;2-MERCAPTOPYRIDINE-N-OXIDE 99%;2-MERCAPTOPYRIDINE N-OXIDE SODIUM SALT ANHYDROUS, 98%;PYRIDINETHIOLOXIDE;Pyrithione (and/or unspecified salts);2-MERCAPTOPYRIDINE-N-OXIDE 90% ,PYRITHIONE 90%
CAS:1121-31-9
MF:C5H5NOS
MW:127.16
EINECS:214-329-4
Product Categories:PYRIDINE
Mol File:1121-31-9.mol
2-Pyridinethiol 1-oxide Chemical Properties
Melting point 69-72 °C (lit.)
Boiling point 350.2±15.0 °C(Predicted)
density 1.255 (estimate)
refractive index 1.5480 (estimate)
storage temp. Refrigerator
solubility Soluble in tris-hydrochloric acid.
form Powder, Crystals, and/or Chunks
pka5.40±0.50(Predicted)
color Off-white to beige or yellow to yellow-greenish or grayish-green
Sensitive Air & Light Sensitive
Merck 14,7994
BRN 906983
Stability:Stable. Incompatible with strong bases, strong oxidizing agents.
CAS DataBase Reference1121-31-9(CAS DataBase Reference)
NIST Chemistry Reference2-Mercaptopyridine-n-oxide(1121-31-9)
EPA Substance Registry System2-Pyridinethiol, 1-oxide (1121-31-9)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-22-63-20/21/22
Safety Statements 26-36-24/25-36/37-22
RIDADR 2811
WGK Germany 3
RTECS UT8999000
8-10-13-23
TSCA Yes
HS Code 29333990
MSDS Information
ProviderLanguage
1-Hydroxy-2(1H)-pyridinethione English
SigmaAldrich English
ACROS English
ALFA English
2-Pyridinethiol 1-oxide Usage And Synthesis
Chemical Propertiesoff-white powder
Uses2-Mercaptopyridine N-oxide is used in ratiometric fluorescence imaging of intracellular zinc ions in mammalian cultures. It is used in the radical coupling of benzoyl derivatives of 2-deoxy-D-ribose, with heterocyclic bases to give C-nucleosides. It acts as a ligand and form coordination complexes with palladium chloride. It is a precursor to O-acyl thiohydroxamates. Further, it serves as an antifungal agent. In addition to this, it is used in the preparation of 1-oxa-2-oxo-3-thia-indolizinium chloride by reaction with carbonyl dichloride.
UsesPrecursor to O-acyl thiohydroxamates. Ligates to metals to form biologically active complexes.
General Description2-Mercaptopyridine N-oxide forms complexes on reaction with palladium chloride. It inhibits NADH-fumarate reductase purified from Trypanosoma cruzi. It is precursor to O-acyl thiohydroxamates. It ligates to metals to form biologically active complexes.
2-Pyridinethiol 1-oxide Preparation Products And Raw materials
Preparation ProductsBispyrithione

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