| 2-Amino-5-chloropyridine Basic information |
| Product Name: | 2-Amino-5-chloropyridine |
| Synonyms: | 2-Amino-5-chloropyridine 5-Chloro-2-pyridineamine;5-Chloro-a-aminopyridine;2-Amino-5-chloropyridine ,98%;2-Amino-5-chloropyridine;2-AMINO-5-CHLOROPYRIDINE 5-CHLORO-PYRIDIN-2-YLAMINE;2-Amino-5-chlorophridine;2-AMINO-5-CHLOROPYRIDINE FOR SYNTHESIS |
| CAS: | 1072-98-6 |
| MF: | C5H5ClN2 |
| MW: | 128.56 |
| EINECS: | 214-020-4 |
| Product Categories: | FINE Chemical & INTERMEDIATES;Amines;PYRIDINE;Nitrogen cyclic compounds;blocks;Heterocycle-Pyridine series;Pyridines, Pyrimidines, Purines and Pteredines;Pyridines derivates;Chloropyridines;Halopyridines;C5Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;amine| alkyl chloride;Bromides;Pyridines;bc0001 |
| Mol File: | 1072-98-6.mol |
| 2-Amino-5-chloropyridine Chemical Properties |
| Melting point | 135-138 °C (lit.) |
| Boiling point | 127-128 °C/11 mmHg (lit.) |
| density | 1.2417 (rough estimate) |
| refractive index | 1.5110 (estimate) |
| Fp | 160 °C |
| storage temp. | 2-8°C |
| solubility | 1.0g/l |
| pka | 4.67±0.13(Predicted) |
| form | Crystalline Powder |
| color | Beige to beige-brown |
| Water Solubility | 1 g/L (20 ºC) |
| BRN | 108735 |
| InChIKey | MAXBVGJEFDMHNV-UHFFFAOYSA-N |
| CAS DataBase Reference | 1072-98-6(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Amino-5-chloropyridine(1072-98-6) |
| EPA Substance Registry System | 2-Amino-5-chloropyridine (1072-98-6) |
| Safety Information |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 22-24/25-37/39-26-36 |
| WGK Germany | 3 |
| Hazard Note | Harmful |
| HazardClass | IRRITANT |
| HS Code | 29333999 |
| MSDS Information |
| Provider | Language |
|---|---|
| 2-Amino-5-chloropyridine | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| 2-Amino-5-chloropyridine Usage And Synthesis |
| Chemical Properties | beige to beige-brown crystalline powder |
| Uses | 5-Chloro-2-pyridinamine is a useful synthetic intermediate. It can be used to synthesize zopiclone (Z700500) which is a cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists. |
| Synthesis Reference(s) | The Journal of Organic Chemistry, 41, p. 93, 1976 DOI: 10.1021/jo00863a020 |
| Purification Methods | Recrystallise this base from pet ether. It sublimes at 50o/0.5mm. [Beilstein 22 II 332, 22/8 V 541.] |
| 2-Amino-5-chloropyridine Preparation Products And Raw materials |
Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.
日本语
한국어
Français
Deutsch
España
Türkiye