Methyl indole-5-carboxylate

Methyl indole-5-carboxylate
  • CAS No.:1011-65-0
Other grades of this product :
Methyl indole-5-carboxylate Basic information
Product Name:Methyl indole-5-carboxylate
Synonyms:INDOLE-5-CARBOXYLIC ACID METHYL ESTER(I5CAMe);Methyl indole-5-carboxylate,99%;Methyl indole-5-carboxyla...;5-(Methoxycarbonyl)indole;H-Indole-5-carboxylic Acid Methyl Ester;5-(Methoxycarbonyl)-1H-indole;Methyl 1H-indol-5-carboxylate;Methyl indole-5-carboxylate in stock Factory
CAS:1011-65-0
MF:C10H9NO2
MW:175.18
EINECS:627-947-8
Product Categories:Indole Derivatives;Indoles and derivatives;blocks;Carboxes;IndolesOxindoles;Indole;Acids and Derivatives;Heterocycles;Indoles;Simple Indoles;Boronic Acid;Heterocyclic Compounds;Building Blocks;Heterocyclic Building Blocks;Indolines ,Indoles ,Indazoles
Mol File:1011-65-0.mol
Methyl indole-5-carboxylate Chemical Properties
Melting point 126-128 °C (lit.)
Boiling point 331.7±15.0 °C(Predicted)
density 1.253±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka16.09±0.30(Predicted)
form powder to crystal
color White to Gray to Brown
Water Solubility Insoluble in water.
BRN 474256
CAS DataBase Reference1011-65-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HazardClass IRRITANT
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
Methyl indole-5-carboxylate Usage And Synthesis
Chemical PropertiesWhite to tan crystalline powder
UsesMethyl indole-5-carboxylate may be used as a reactant in the following processes:
  • biosynthesis of inhibitors of protein kinases
  • metal-free Friedel-Crafts alkylation
  • preparation of diphenylsulfonium ylides from Martin′s sulfurane
  • cross dehydrogenative coupling reactions
  • synthesis of indirubin derivatives
  • preparation of aminoindolylacetates
General DescriptionMethyl indole-5-carboxylate (Methyl 1H-indole-5-carboxylate), a substituted 1H-indole, can be prepared by the esterification of indole-5-carboxylic acid. Its efficacy as a substrate for indigoid generation has been assessed.
Methyl indole-5-carboxylate Preparation Products And Raw materials
Preparation Products1-METHYL-1H-INDOLE-5-CARBOXYLIC ACID-->INDOLE-5-METHANOL-->methyl indoline-5-carboxylate-->2,3-DIHYDRO-1H-INDOLE-5-CARBOXYLIC ACID

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