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| ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Basic information |
| ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Chemical Properties |
| Melting point | 245-250 °C(lit.) | | Boiling point | 324.41°C (rough estimate) | | density | 1.3175 (rough estimate) | | refractive index | 1.5400 (estimate) | | storage temp. | 2-8°C | | solubility | methanol: 10 mg/mL, clear | | form | powder | | pka | 0.85±0.10(Predicted) | | color | yellow | | BRN | 3271427 | | InChIKey | AFVLVVWMAFSXCK-VMPITWQZSA-N | | CAS DataBase Reference | 28166-41-8(CAS DataBase Reference) |
| ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Usage And Synthesis |
| Chemical Properties | yellow crystalline powder | | Uses | inhibitor of mitochondrial pyruvate transport | | Uses | α-Cyano-4-hydroxycinnamic acid (CHC) was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays. | | Uses | α-Cyano-4-hydroxycinnamic acid(CHC) was used as a matrix for peptides and nucleotides in mass spectroscopic analysis. It was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays. | | General Description | α-Cyano-4-hydroxycinnamic acid is the commonly used matrix for analyzing peptides by matrix-assisted laser desorption/ionization mass spectrometry. It inhibits the monophenolase activity and diphenolase activity of mushroom tyrosinase. | | Biochem/physiol Actions | α-Cyano-4-hydroxycinnamic acid acts as a specific inhibitor of monocarboxylic acid transport, including lactate and pyruvate transport. It is also reported to block β-cell apical anion exchange (IC50 of 2.4 mM). |
| ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Preparation Products And Raw materials |
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