p-(2-Methoxyethyl) phenol

CAS No.：56718-71-9

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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p-(2-Methoxyethyl) phenol Basic information

Product Name:	p-(2-Methoxyethyl) phenol
Synonyms:	P-ethyl ether;P-Methyl ether;Metoprolol Tartrate EP IMpurity-B;Metoprolol EP IMpurity B;Phenol,4-(2-Methoxyethyl)-;The Methoxy ethyl phenol;4-(2-Methoxyethyl)Phenol (56781-17-9);p-Hydroxyphenethyl methyl ether
CAS:	56718-71-9
MF:	C9H12O2
MW:	152.19
EINECS:	260-354-9
Product Categories:	Intermediates & Fine Chemicals;Various Metabolites and Impurities;Phenoles and thiophenoles;Metabolites & Impurities;Pharmaceuticals;Organic Building Blocks;Aromatic Phenols;Oxygen Compounds;Phenols;Aromatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:	56718-71-9.mol

p-(2-Methoxyethyl) phenol Chemical Properties

Melting point	42-45 °C(lit.)
Boiling point	125 °C / 3mmHg
density	1.060±0.06 g/cm3(Predicted)
vapor pressure	0.41Pa at 20℃
Fp	>230 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	10.00±0.15(Predicted)
color	White to Off-White
Water Solubility	8.42g/L at 20℃
LogP	1.79 at 20℃
CAS DataBase Reference	56718-71-9(CAS DataBase Reference)
EPA Substance Registry System	Phenol, 4-(2-methoxyethyl)- (56718-71-9)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
HS Code	29095000

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

p-(2-Methoxyethyl) phenol Usage And Synthesis

Chemical Properties	White Low Melting Solid
Uses	4-(2-Methoxyethyl)phenol is an Impurity of Metoprolol.
Uses	4-(2-Methoxyethyl)phenol may be used in the preparation of methyl analog of metoprolol (MAM).
General Description	4-(2-Methoxyethyl)phenol can be prepared by reacting methyl vinyl ether and 4-bromonitrobenzene.

p-(2-Methoxyethyl) phenol Preparation Products And Raw materials

Raw materials	Phenethyl alcohol
Preparation Products	4-(2-Methoxyethyl)Phenol

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