Other grades of this product :
| Rolapitant Basic information |
| Product Name: | Rolapitant | | Synonyms: | Rolapitant;(5S,8S)-8-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one hydrochloride.;Rolapitant HCl;Rolapitant(sch619734);(5S,8S)-8-[[[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethyl]oxy]methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one;(5S,8S)-8-({(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one;rolapitant,914462-92-3;1,7-Diazaspiro[4.5]decan-2-one,8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-,(5S,8S)- | | CAS: | 552292-08-7 | | MF: | C25H26F6N2O2 | | MW: | 500.48 | | EINECS: | 812-147-5 | | Product Categories: | | Mol File: | 552292-08-7.mol |
| Rolapitant Chemical Properties |
| Boiling point | 523.5±50.0 °C(Predicted) | | density | 1.34±0.1 g/cm3(Predicted) | | pka | 15.88±0.40(Predicted) |
| Rolapitant Usage And Synthesis |
| Definition | ChEBI: An azaspiro compound that is 1,7-diazaspiro[4.5]decan-2-one carrying additional phenyl and 1-{[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl substituents at position 8. Used (in the form of the hydrochloride hydrate) for the prevention of delayed nausea and
vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy. |
| Rolapitant Preparation Products And Raw materials |
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