6-Methylpurine

CAS No.：2004-03-7

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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6-Methylpurine Basic information

Product Name:	6-Methylpurine
Synonyms:	6-Methyl-7H-purine;6-Methylpurine,98%;NSC 407198;6-METHYLPURINE;6-methyl-1h-purin;6-Methyl-1H-purine;6-Methyl-9H-purine;6-methyl-purin
CAS:	2004-03-7
MF:	C6H6N4
MW:	134.14
EINECS:	217-903-2
Product Categories:	Nucleotides and Nucleosides;Bases & Related Reagents;Nucleotides;Biochemicals and Reagents;Nucleoside Analogs;Nucleosides, Nucleotides, Oligonucleotides;PYRIMIDINE
Mol File:	2004-03-7.mol

6-Methylpurine Chemical Properties

Melting point	237-238 °C(lit.)
Boiling point	237.24°C (rough estimate)
density	1.2769 (rough estimate)
refractive index	1.7000 (estimate)
storage temp.	-20°C
pka	9.25±0.20(Predicted)
color	off-white
CAS DataBase Reference	2004-03-7
NIST Chemistry Reference	1H-Purine, 6-methyl-(2004-03-7)
EPA Substance Registry System	1H-Purine, 6-methyl- (2004-03-7)

Safety Information

Hazard Codes	Xn,T
Risk Statements	22-41-43-23/24/25-27
Safety Statements	26-36/37/39-45-39-36/37-28
RIDADR	2811
WGK Germany	3
RTECS	UO8700000
HS Code	29339900

MSDS Information

Provider	Language
ACROS	English

6-Methylpurine Usage And Synthesis

Chemical Properties	Light Yellow Powder
Uses	6-Methylpurine (MeP) is a toxic adenine analog used as a bisubstrate inhibitor of enzymes that bind adenosyl moieties and which may become phosphorylated to levels that inhibit RNA and protein synthesis.
Definition	ChEBI: Purine bearing a methyl substituent at position 6.
Synthesis Reference(s)	Journal of the American Chemical Society, 95, p. 6407, 1973 DOI: 10.1021/ja00800a042

6-Methylpurine Preparation Products And Raw materials

Raw materials	Diethyl ether-->Ammonia-->Palladium-->4,6-Dichloro-5-nitropyrimidine-->1,1-diethoxyethylene-->Diethoxymethyl acetate
Preparation Products	7-METHYLGUANINE

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