Other grades of this product :
| Avibactam INT 1 Basic information | | Uses |
| Product Name: | Avibactam INT 1 | | Synonyms: | Avibactam Intermediate;Avibactam INT 1;(2S,5R)-Methyl-5-[(benzyloxy)amino]piperidine-2-carboxylate ethanedioate;(2S, 5R) -benzyloxyaminopiperidine-2-carboxylic acid ethyl oxalate;Avibactam IM-1;Avivabine sodium intermediate 1;Avibactam-002-oxalate;ethyl(2S,5R)-5-((benzyloxy)amino)piperdine-2-carboxylate oxalate | | CAS: | 1416134-48-9 | | MF: | C17H24N2O7 | | MW: | 368.39 | | EINECS: | | Product Categories: | intermediate | | Mol File: | 1416134-48-9.mol |
| Avibactam INT 1 Chemical Properties |
| storage temp. | Inert atmosphere,Room Temperature |
| Avibactam INT 1 Usage And Synthesis |
| Uses | (2S,5R)-5-[(Phenylmethoxy)amino]-2-piperidinecarboxylic Acid Ethyl Ester Ethanedioate is an impurity of Avibactam; a novel β-lactamase inhibitor with a non-lactam structural scaffold. Avibactam irreversibly inhibits lactamase from Mycobacterium tuberculosis. | | Uses | (2S,5R)-5-[(Phenylmethoxy)amino]-2-piperidinecarboxylic Acid Ethyl Ester Ethanedioate is an impurity of Avibactam (A794850, Na Salt); a novel β-lactamase inhibitor with a non-lactam structural scaffold. Avibactam irreversibly inhibits lactamase from Mycobacterium tuberculosis. |
| Avibactam INT 1 Preparation Products And Raw materials |
| Raw materials | (S)-ethyl 2-((tert-butoxycarbonyl)amino)-6-(dimethylhydrosulfinyl)-5-hydroxyhex-5-enoate-->Avibactam Impurity 15-->(S)-ethyl 4-(chloromethyl)-11,11-dimethyl-9-oxo-1-phenyl-2,10-dioxa-3,8-diazadodec-3-ene-7-carboxylate-->L-Norleucine, 6-chloro-N-[(1,1-dimethylethoxy)carbonyl]-5-[(phenylmethoxy)imino]-, phenylmethyl ester-->Benzyl (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxylate ethanedioate-->2-Piperidinecarboxylic acid, 5-[(phenylmethoxy)imino]-, phenylmethyl ester, (2S)--->BOC-L-PYROGLUTAMIC ACID BENZYL ESTER-->Sodium ethoxide-->Ethanol-->Oxalic acid | | Preparation Products | AvibactaM |
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