Product

N-alpha-FMOC-Nepsilon-BOC-L-Lysine

CAS No.：71989-26-9

Other grades of this product :

N-alpha-FMOC-Nepsilon-BOC-L-Lysine Basic information

Product Name:	N-alpha-FMOC-Nepsilon-BOC-L-Lysine
Synonyms:	N^α-FMoc-N^ε-Boc-L-lysine;(S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-6-((tert-butoxycarbonyl)aMino)hexanoic acid;N^e-Boc-N^a-FMoc-L-lysine, 98%;ALPHA-FMOC-EPSILON-BOC-LYSINE;fmoc-lys(boc)-o;Nα-Fmoc-Nε-Boc-L-lysine;L-LYSINE, N6-[(1,1-DIMETHYLETHOXY)CARBONYL]-N2-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-;FMOC-D-LYS(BOC)
CAS:	71989-26-9
MF:	C26H32N2O6
MW:	468.54
EINECS:	276-256-4
Product Categories:	Amino Acid Derivatives;Amino Acids;Lysine [Lys, K];Fmoc-Amino Acids and Derivatives;Amino Acids (N-Protected);Biochemistry;Boc-Amino Acids;Fmoc-Amino Acids;Fmoc-Amino acid series
Mol File:	71989-26-9.mol

N-alpha-FMOC-Nepsilon-BOC-L-Lysine Chemical Properties

Melting point	130-135 °C (dec.)
alpha	-12 º (c=2,DMF 24 ºC)
Boiling point	570.69°C (rough estimate)
density	1.2301 (rough estimate)
refractive index	-12 ° (C=1, DMF)
storage temp.	Store below +30°C.
form	Powder
pka	3.88±0.21(Predicted)
color	White
optical activity	[α]20/D 12±1°, c = 1% in DMF
Water Solubility	Slightly soluble in water.
BRN	4217767
Stability:	Stable. Incompatible with strong oxidizing agents.
InChIKey	UMRUUWFGLGNQLI-QFIPXVFZSA-N
CAS DataBase Reference	71989-26-9(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Safety Statements	24/25-36/37/39-27-26
WGK Germany	3
HS Code	29224999

MSDS Information

Provider	Language
N-alpha-FMOC-Nepsilon-BOC-L-Lysine	English
SigmaAldrich	English
ACROS	English

N-alpha-FMOC-Nepsilon-BOC-L-Lysine Usage And Synthesis

Chemical Properties	white to light yellow crystal powde
Uses	It is used to prepare dimeric RGD peptide-paclitaxel conjugate as model for integrin-targeted drug delivery. It is also used to synthesize DOTA-conjugated multivalent cyclic-RGD peptide dendrimers for tumor targeting and imaging use.
Uses	Fmoc-Lys(Boc)-OH can be used for: The solid-phase synthesis of pentasubstituted dihydroimidazolylbutyl dihydroimidazol-3-ium salts by coupling with p-methylbenzhydrylamine (MBHA) resin. Fmoc-based peptide synthesis of bis-naphthalene diimide, a threading intercalator. Synthesis of ε-Boc-ε-(3,5-bis-trifluoromethyl-benzyl)-α-Fmoc-L-Lysine to be used as ¹⁹F NMR based screening tool.

N-alpha-FMOC-Nepsilon-BOC-L-Lysine Preparation Products And Raw materials

Preparation Products

FMOC-LYS(TEOC)-OH-->L-Lysine, N6-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]--->FMOC-LYS(BIOTIN)-OH-->Fmoc-L-Lys(Dde)-OH

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