2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one

CAS No.：20348-09-8

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one Basic information

Product Name:	2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one
Synonyms:	LABOTEST-BB LT00451615;2H-PYRIDO[3,2-B]-1,4-OXAZIN-3(4H)-ONE;TIMTEC-BB SBB006815;2H-PYRIDO(3,2-B)-1,4-OXAZIN-3(4H)-ONE 95 %;4H-Pyrido[3,2-b][1,4]oxazin-3-one;3,4-Dihydro-2H-pyrido[3,2-b]-1,4-oxazine-3-one;2,3-dihydro-3-oxo-4H-pyrido[3,2-b]-1,4-oxazine;4H-pyrido[2,3-e][1,4]oxazin-3-one
CAS:	20348-09-8
MF:	C7H6N2O2
MW:	150.13
EINECS:	243-751-1
Product Categories:	C7 and C8;Heterocyclic Building Blocks;Pyridines, Pyrimidines, Purines and Pteredines;Heterocyclic Compounds;Pyridines
Mol File:	20348-09-8.mol

2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one Chemical Properties

Melting point	204-206 °C(lit.)
Boiling point	384.2±37.0 °C(Predicted)
density	1.327±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	11.06±0.20(Predicted)
BRN	1074010
CAS DataBase Reference	20348-09-8(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-37/39
WGK Germany	3
HazardClass	IRRITANT
HS Code	2933998090

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one Usage And Synthesis

Uses	2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one was used in the synthesis of quinazolinbenzoxazine derivatives.

2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one Preparation Products And Raw materials

Raw materials

Acetonitrile, 2-[(2-nitro-3-pyridinyl)oxy]--->6-BROMO-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE-->3-Oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-6-carbaldehyde-->2-Amino-3-hydroxypyridine-->tert-Butyl bromoacetate-->carbon monoxide-->3-Hydroxy-2-nitropyridine-->Ethyl bromoacetate-->Chloroacetyl chloride-->Chloroacetic acid

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