Other grades of this product :
| (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride Basic information |
| Product Name: | (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride | | Synonyms: | (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride;(R)-alpha-[[[2-(4-AMinophenyl)ethyl]aMino]Methyl];(R)-2-[2-(4-Amino-phenyl)-ethylamino]-1-phenyl-ethanol HCl;(R)-[[[2-(4-aMinophenyl)ethyl]aMino]Methyl]- BenzeneMethanol HCl;(R)--[[[2-(4-aminophenyl)ethyl]amino]methyl]-Benzenemethanol;Mirabegron INT 3;(R) -2 - [[2- (4- aminophenyl) ethyl] amino] -1-phenylethanol hydrochloride;(R)-2-((4-AMinophenethyl)aMino)-1-phenylethanol hydrochloride | | CAS: | 521284-22-0 | | MF: | C16H21ClN2O | | MW: | 292.81 | | EINECS: | 700-425-8 | | Product Categories: | | Mol File: | 521284-22-0.mol |
| (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride Chemical Properties |
| density | 1145 at 20℃ | | vapor pressure | 0.015Pa at 25℃ | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | form | Powder | | LogP | -1.35 at 20℃ and pH5.79 |
| (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride Usage And Synthesis |
| Uses | (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes. | | Synthesis | A mixture of (100 g) (R)-2-[2’ -(4-nitrophenyl)ethyl]amino] -1 -phenylethanol monohydroch bride (prepared according to example Ib), methanol (2000 mL) and Raney Nickel (20 g, wet) was stirred under hydrogen pressure (60 psi) for 6 hrs. The reaction solution was filtered, and the filtrate was concentrated in vacuo. The residue was mixed with isopropanol (300 mL) and reaction mixture was heated to 78°C (±2). The mixture was added to toluene (900 mL). The reaction mixture was gradually cooled to 28°C (±2) and stirred at this temperature for 3 hrs. The solid obtained was filtered, washed with toluene and dried under vacuo at 48°C (±2) to obtain (R)-2-[[2-(4-aminophenyl)ethyl]-amino]- I -phenylethanol monohydrochioride.Yield: 78.1 g (86.1%); Purity by HPLC: 99.14 %. |
| (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride Preparation Products And Raw materials |
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![(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride](/img/521284-22-0.jpg "(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride")
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