5-Bromo-2,4-dichloropyrimidine

5-Bromo-2,4-dichloropyrimidine
  • CAS No.:36082-50-5
Other grades of this product :
5-Bromo-2,4-dichloropyrimidine Basic information
Product Name:5-Bromo-2,4-dichloropyrimidine
Synonyms:BUTTPARK 48\06-22;5-BROMO-2,4-DICHLOROPYRIMIDINE;TIMTEC-BB SBB003301;5-Bromo-2,4-Dichloropyridimidine;5-BROMO-2,4-DICHLOROPYRIMIDINE 99%;2,4-DICHLORO-5-BROMO PYRIMIDINE;5-Bromo-2,4-dichL;5-Bromo-2,4-dichloropyrimidine ,97%
CAS:36082-50-5
MF:C4HBrCl2N2
MW:227.87
EINECS:629-358-1
Product Categories:Building Blocks;C4 to C5;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;Heterocycle-Pyrimidine series;Pyrimidine Series;pharmacetical;Halides;Pyrazines, Pyrimidines & Pyridazines;Pyrimidine;Heterocyclic Building Blocks;Pyrimidines;PyrimidinesHeterocyclic Building Blocks;Pyridines, Pyrimidines, Purines and Pteredines;Halogenated;Organohalides;Nucleotides and Nucleosides;Aromatics Compounds;Bases & Related Reagents;Nucleotides;Aromatics;Pyrazines, Pyrimidines & Pyridazines;Building Blocks;Halogenated Heterocycles
Mol File:36082-50-5.mol
5-Bromo-2,4-dichloropyrimidine Chemical Properties
Melting point 29-30 °C (lit.)
Boiling point 128 °C/15 mmHg (lit.)
density 1.781 g/mL at 25 °C (lit.)
refractive index n20/D 1.603(lit.)
Fp >230 °F
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Ether (Slightly), Ethyl Acetate (Slightly), Toluene (Slig
form Liquid or Low Melting Solid
pka-4.26±0.29(Predicted)
Specific Gravity1.781
color Clear colorless to light yellow
BRN 124441
InChIKeySIKXIUWKPGWBBF-UHFFFAOYSA-N
CAS DataBase Reference36082-50-5(CAS DataBase Reference)
Safety Information
Hazard Codes T,C
Risk Statements 23/24/25-34-43
Safety Statements 26-27-36/37/39-45
RIDADR UN 3263 8/PG 2
WGK Germany 3
Hazard Note Toxic/Corrosive
HazardClass 8
PackingGroup III
HS Code 29335990
MSDS Information
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5-Bromo-2,4-dichloropyrimidine English
SigmaAldrich English
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5-Bromo-2,4-dichloropyrimidine Usage And Synthesis
Chemical PropertiesColourless Oil
UsesStarting material for the synthesis of trisubstituted pyrimidines via a combination of nucleophilic substitution and palladium-catalyzed aryl cross-coupling.1
Uses5-Bromo-2,4-dichloropyrimidine may be employed as starting reagent for the synthesis of positive allosteric modulators for GABAB receptors (drug-like class of compounds) and pyridinepyrimidine analogs.
General Description5-Bromo-2,4-dichloropyrimidine is a halogenoprimidine. It has been reported as an intermediate during the synthesis of 2,4-di-t-butoxy-5-bromopyrimidine and 2,4-di-t-butoxy-5-pyrimidineboronic acid.

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