2-Chloro-5-chloromethylpyridine

CAS No.：70258-18-3

Other grades of this product :

2-Chloro-5-chloromethylpyridine Basic information

Description Sources

Product Name:	2-Chloro-5-chloromethylpyridine
Synonyms:	2-CHLORO-5-CHLOROMETHYLPYRIDINE 90%;2-Chloro-5-ChloroMethylPyridine(Ccmp)98%;2-Chloro-5-Chloro Methyl Pyridine (Ccmp) 98%;Pyridine, 2-chloro-5-(chloromethyl)- (9CI);2-Chloro-5-chloromethylpyridine, tech., 90%;imidacloprid impurity;2-CHLORO-5-(CHLOROMETHYL)PYRIDINE[FOR IMIDACLOPRID];2-CHLORO-5-CHLOROMETHYLPYRIDINE 2-CHLORO-5-CHLOROMETHYLPYRIDINE
CAS:	70258-18-3
MF:	C6H5Cl2N
MW:	162.02
EINECS:	615-091-8
Product Categories:	Pharmaceutical intermediates;C6Heterocyclic Building Blocks;Pyridines;Chloropyridines;Halogenated Heterocycles;Heterocyclic Building Blocks;HALOMETYL;Pyridine;Pyridine series;Methyl Halides;Halopyridines;Methyl Halides;API Intermediate;Heterocycle-Pyridine series
Mol File:	70258-18-3.mol

2-Chloro-5-chloromethylpyridine Chemical Properties

Melting point	37-42 °C(lit.)
Boiling point	267.08°C (rough estimate)
density	1.4411 (rough estimate)
refractive index	1.6000 (estimate)
Fp	>230 °F
storage temp.	Inert atmosphere,2-8°C
form	Moist Crystals
pka	-0.75±0.10(Predicted)
color	Beige
Water Solubility	Insoluble in water.
BRN	1635690
InChIKey	SKCNYHLTRZIINA-UHFFFAOYSA-N
CAS DataBase Reference	70258-18-3(CAS DataBase Reference)

Safety Information

Hazard Codes	C,Xi,F
Risk Statements	22-34-36-10
Safety Statements	26-36/37/39-45-25-36-16
RIDADR	UN 3261 8/PG 2
WGK Germany	3
Hazard Note	Corrosive/Harmful
HazardClass	LACHRYMATOR, CORROSIVE
HazardClass	8
PackingGroup	II
HS Code	29333999

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English
ALFA	English

2-Chloro-5-chloromethylpyridine Usage And Synthesis

Description	2-Chloro-5-chloromethylpyridine is used for the synthesis of various pharmaceutical compounds. It can also be used for the synthesis of new neonicotinoid compounds¹, having insecticidal activity. It is the raw material of pesticide products such as imidacloprid, acetamiprid as well as bactericide and herbicide^2,3.
Sources	https://www.alfa.com/en/catalog/L19284/ https://www.trc-canada.com/product-detail/?C364715 www.szqhbio.com/wap_news_detailen/id/1.htm
Chemical Properties	beige moist crystals
Uses	2-Chloro-5-(chloromethyl)pyridine is used for the synthesis of various pharmaceutical compounds. It can also be used for the synthesis of new neonicotinoid compounds.

2-Chloro-5-chloromethylpyridine Preparation Products And Raw materials

Raw materials

Phosphorus pentoxide-->Nicotinic acid-->1,3-Cyclopentadiene-->2-Chloro-5-methylpyridine-->2-Chloro-5-trichloromethylpyridine-->3-(Chloromethyl)pyridine-->Pentanenitrile, 4-chloro-4-(chloromethyl)-5-oxo--->Pentanamide, 4-chloro-4-(chloromethyl)-5-oxo--->2-Chloro-5-hydroxymethylpyridine-->(6-methoxypyridin-3-yl)methanol-->5-(hydroxymethyl) pyridin-2(1H)-one-->N,N-Dibutylformamide-->Methyl 6-chloronicotinate-->6-Chloronicotinic acid-->Cyanuric chloride

Preparation Products

Acetamiprid

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