2,4-DICHLORO-1-NAPHTHOL

CAS No.：2050-76-2

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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2,4-DICHLORO-1-NAPHTHOL Basic information

Product Name:	2,4-DICHLORO-1-NAPHTHOL
Synonyms:	2,4-DICHLORONAPHTHOL;2,4-DICHLORO-1-NAPHTHOL 99%;2,4-Dichloro-1-naphthol [for photography];2,4-Dichloronaphthalen-1-ol;2,4-Dichloro-1-naphthol,99%;[for photography];2,4-Dichloro-1-naphthol AURORA KA-5007
CAS:	2050-76-2
MF:	C10H6Cl2O
MW:	213.06
EINECS:	218-103-6
Product Categories:	Organic Building Blocks;Oxygen Compounds;Industrial/Fine Chemicals;Aromatic Halides (substituted);Phenols
Mol File:	2050-76-2.mol

2,4-DICHLORO-1-NAPHTHOL Chemical Properties

Melting point	104-107 °C(lit.)
Boiling point	305.89°C (rough estimate)
density	1.2937 (rough estimate)
vapor density	7.3 (vs air)
refractive index	1.5500 (estimate)
storage temp.	2-8°C
solubility	pyridine: soluble5%, clear, colorless to dark yellow
form	powder
color	off-white to tan
CAS DataBase Reference	2050-76-2(CAS DataBase Reference)
EPA Substance Registry System	1-Naphthalenol, 2,4-dichloro- (2050-76-2)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
HS Code	29081990

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English

2,4-DICHLORO-1-NAPHTHOL Usage And Synthesis

Chemical Properties	beige-yellowish crystalline powder
Uses	2,4-Dichloro-1-naphthol has been used in: spectrophotometric determination of arginine with previous modifications of the Sakaguchi reaction guanidinoacetate and guanidinosuccinate assay of urine, an indicator of kidney dysfunction
Purification Methods	Crystallise the naphthol pKEst from MeOH. The 1-methyl ether has m 58o (from EtOH). [Beilstein 6 H 612, 6 I 308, 6 II 582, 6 III 2934, 6 IV 4233.]

2,4-DICHLORO-1-NAPHTHOL Preparation Products And Raw materials

Raw materials	1(2H)-Naphthalenone, 2,2,4-trichloro--->1,2,3,4-Tetrachloro-1,2,3,4-tetrahydronaphthalene-->1-Naphthalenol, 2-chloro--->Chlorine-->Naphthalene-->1-Naphthol-->Acetic acid
Preparation Products	2-Chloro-1,4-naphthoquinone-->4-CHLORO-1-NAPHTHOL

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