5-CHLOROTHIOPHENE-2-CARBOXYLIC ACID

5-CHLOROTHIOPHENE-2-CARBOXYLIC ACID
  • CAS No.:24065-33-6
Other grades of this product :
5-CHLOROTHIOPHENE-2-CARBOXYLIC ACID Basic information
Product Name:5-CHLOROTHIOPHENE-2-CARBOXYLIC ACID
Synonyms:5-CHLOROTHIOPHENE-2-CARBOXYLIC ACID;5-CHLORO-2-THIOPHENECARBOXYLIC ACID;AKOS B000092;2-Thiophenecarboxylic acid, 5-chloro-;5-chloro-2-thiophenecarboxylicaci;Chlorothiophene-2-carboxy;5-Chlorothiophene-2-carboxylic Acid, 97+%;Rivaroxaban Impurity N
CAS:24065-33-6
MF:C5H3ClO2S
MW:162.59
EINECS:000-000-0
Product Categories:Intermediate of Rivaroxaban;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Sulfur & Selenium Compounds;Thiophene&Benzothiophene;Miscellaneous;Halogenated Heterocycles;Heterocyclic Building Blocks;Thiophenes;ThiophenesBuilding Blocks;Intermediates;Heterocycle-oher series;bc0001
Mol File:24065-33-6.mol
5-CHLOROTHIOPHENE-2-CARBOXYLIC ACID Chemical Properties
Melting point 154-158 °C(lit.)
Boiling point 287.0±20.0 °C(Predicted)
density 1.466 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka3.32±0.10(Predicted)
form Powder
color Cream-yellow
BRN 118361
InChIKeyQZLSBOVWPHXCLT-UHFFFAOYSA-N
CAS DataBase Reference24065-33-6(CAS DataBase Reference)
NIST Chemistry Reference5-Chloro-2-thiophenecarboxylic acid(24065-33-6)
Safety Information
Hazard Codes Xi
Risk Statements 36-43-36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
RTECS XM8400000
HazardClass IRRITANT
HS Code 29349990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
5-CHLOROTHIOPHENE-2-CARBOXYLIC ACID Usage And Synthesis
Chemical PropertiesWhite to light yellow crystal powder
UsesA metabolite of Rivaroxaban (R538000).
Uses5-Chlorothiophene-2-carboxylic acid can be used in the synthesis of the following:
  • rivaroxaban, an oxazolidinone derivative used in the treatment of thromboembolic disorders
  • 5-chloro-4-nitrothiophene-2-carboxylic acid, which can be used in the synthesis of thieno[2,3-b][1,4]thiapezine-5-ones

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