6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one

CAS No.：1016636-76-2

Other grades of this product :

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Basic information

Use

Product Name:	6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
Synonyms:	6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-on;6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one;Pyrido[2,3-d]pyriMidin-7(8H)-one, 6-broMo-2-chloro-8-cyclopentyl-5-Methyl-;Palbociclib-015;6-bromo-2-chloro-8-cyclopentyl-5-methylpyridino[2,3-d]pyrimidin-7(8H)-one;6-broMo-2-chloro-8-cyclopentyl-5-;6-BroMo-2-chloro-8-cyclopentyl-5-Methyl-8H-pyrido[2,3-d]pyriMidin-7-one;PALBOCICLIB-PB3
CAS:	1016636-76-2
MF:	C13H13BrClN3O
MW:	342.62
EINECS:	800-433-2
Product Categories:	Palbociclib;PD 0332991;Anticancer
Mol File:	1016636-76-2.mol

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Chemical Properties

Melting point	190-192°C
Boiling point	468.4±45.0 °C(Predicted)
density	1.645±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly, Sonicated
pka	-0.61±0.20(Predicted)
form	Solid
color	White

Safety Information

Hazard Codes	T
Risk Statements	25
Safety Statements	45
RIDADR	UN2811

MSDS Information

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Usage And Synthesis

Use	6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivatives as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases.
Uses	6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivatives as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases.

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Preparation Products And Raw materials

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