N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester
  • CAS No.:286961-14-6
Other grades of this product :
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester Basic information
Product Name:N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester
Synonyms:N-BOC-1,2,5,6-TETRAHYDROPYRIDINE-4-(PINACOLATO)BORONATE;(N-TERT-BUTOXYCARBONYL)-1,2,3,6-TETRAHYDROPYRIDINE-4-BORONIC ACID PINACOL ESTER;4-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)-3,6-DIHYDRO-2H-PYRIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;3,6-DIHYDRO-2H-PYRIDINE-1-TERT-BUTOXYCARBONYL-4-BORONIC ACID, PINACOL ESTER;1-N-BOC-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-3,6-DIHYDRO-2H-PYRIDINE;1-N-BOC-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-3,6-DIHYDRO-2H-PYRIDINE 98+%;N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester;tert-butyl 1-Boc-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine
CAS:286961-14-6
MF:C16H28BNO4
MW:309.21
EINECS:689-148-0
Product Categories:API intermediates;Organoborons;Pyridine
Mol File:286961-14-6.mol
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester Chemical Properties
Melting point 114.0 to 118.0 °C
Boiling point 348.0±52.0 °C(Predicted)
density 1.05±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka-1.21±0.40(Predicted)
form Solid
color white to off-white
Water Solubility Soluble in most organic solvents. Insoluble in water.
InChIKeyVVDCRJGWILREQH-UHFFFAOYSA-N
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37-60
WGK Germany 3
TSCA No
HazardClass IRRITANT
HS Code 29349990
MSDS Information
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester Usage And Synthesis
Chemical Propertiesoff-white powder
UsesReagent used for suzuki-Miyaura cross-coupling using palladium phosphine catalyst, palladium-catalyzed ligand-controlled regioselective Suzuki coupling, wrenchnolol derivative optimized for gene activation in cells. Also used in Preparation of several enzymatic inhibitors and receptor ligands, orally active anaplastic lymphoma kinase inhibitors and oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes.
UsesN-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester is an intermediate for organic synthesis and pharmaceutical research and development, and can be used for suzuki reaction.
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester Preparation Products And Raw materials

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