Product

2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylthio-1H-benzimidazole

CAS No.：103577-40-8

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2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylthio-1H-benzimidazole Basic information

Product Name:	2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylthio-1H-benzimidazole
Synonyms:	2-[[3-Methyl-4-(2,2,2-trifluoroethoxy)pyridine-2-yl]methylthio]-1H-benzoimidazole;2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinylmethylthio]-1H-benzoimidazole;2-[3-Methyl-4-(2,2,2;Lansoprazole Related Compound B (25 mg) (2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-pyridin-2-yl]methyl]sulfanyl]-1H-benzimidazole);2-{[3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]Methyl}-1H-1,3-benzodiazole-1-thiol;2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)Methyl)thio)-1H-benzo[d]iMidazole;2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]Methyl]thio]-;1H-BenziMidazole, 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]Methyl]thio]-
CAS:	103577-40-8
MF:	C16H14F3N3OS
MW:	353.36
EINECS:	1533716-785-6
Product Categories:	Heterocycles;Intermediates & Fine Chemicals;Imidazol&Benzimidazole;Metabolites & Impurities;Pharmaceuticals;Lansoprazole;(intermediate of lansoprazole);Heterocyclic Compounds
Mol File:	103577-40-8.mol

2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylthio-1H-benzimidazole Chemical Properties

Melting point	149-150°C
Boiling point	494.9±55.0 °C(Predicted)
density	1.41
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	DMSO (Slightly), Methanol (Slightly)
pka	10.60±0.10(Predicted)
form	Crystalline Powder
color	White to Pale Orange
λmax	292nm(EtOH)(lit.)
CAS DataBase Reference	103577-40-8(CAS DataBase Reference)

Safety Information

Safety Statements	24/25
HS Code	29309090

MSDS Information

2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylthio-1H-benzimidazole Usage And Synthesis

Chemical Properties	Pale Yellow Solid
Uses	A metabolite of Lansoprazole, as gastric pump inhibitor
Uses	Lansoprazole Sulfide (Lansoprazole EP Impurity C; USP Impurity B) is a metabolite of Lansoprazole, as gastric pump inhibitor.

2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylthio-1H-benzimidazole Preparation Products And Raw materials

Raw materials	2-Hydroxymethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine hydrochloride-->2, 3-Dimethyl-4-(2,2,2-Trifluoroethpxy) Pyridine-N-Oxide-->Lansoprazole-->2-CHLOROMETHYL-3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)PYRIDINE-->4-Nitro-2,3-lutidine-N-oxide-->1H-BENZOIMIDAZOLE-2-THIOL
Preparation Products	R-(+)-Lansoprazole-->(S)-Lansoprazole

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