4-(4-AMINOPHENYL)MORPHOLIN-3-ONE Five Chongqing Chemdad Co. ，Ltd

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4-(4-AMINOPHENYL)MORPHOLIN-3-ONE

CAS No.：438056-69-0

Other grades of this product :

4-(4-AMINOPHENYL)MORPHOLIN-3-ONE Basic information

Product Name:	4-(4-AMINOPHENYL)MORPHOLIN-3-ONE
Synonyms:	Rivaroxaban Intermediate 1;Rivaroxaban InterMediate;4-(4-aMinophenyl) Morpholinone;3-Morpholinone, 4-(4-aminophenyl)-;4-(4-Aminophenyl)morpholin-3-one ,97%;4-(4-AMinophenyl)-3-Morpholinone;4-(3-Oxo-4-Morpholinyl)aniline;4-(3-Oxo-4-Morpholinyl)aniline-d4
CAS:	438056-69-0
MF:	C10H12N2O2
MW:	192.21
EINECS:	610-147-8
Product Categories:	Amines and Anilines;Heterocycles;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Intermediates;Intermediate of Rivaroxaban
Mol File:	438056-69-0.mol

4-(4-AMINOPHENYL)MORPHOLIN-3-ONE Chemical Properties

Melting point	171.0 to 175.0 °C
Boiling point	502.3±45.0 °C(Predicted)
density	1.268
vapor pressure	0Pa at 25℃
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO (Slightly), Methanol (Slightly, Heated)
form	Solid
pka	4.85±0.10(Predicted)
color	White to Light Brown
Water Solubility	16.6g/L at 20℃
InChIKey	MHCRLDZZHOVFEE-UHFFFAOYSA-N
LogP	-0.8 at 25℃
CAS DataBase Reference	438056-69-0

Safety Information

Safety Statements	24/25
HazardClass	IRRITANT
HS Code	29349990

MSDS Information

4-(4-AMINOPHENYL)MORPHOLIN-3-ONE Usage And Synthesis

Chemical Properties	4-(4-AMINOPHENYL)MORPHOLIN-3-ONE is Off-White Solid
Uses	4-(4-AMINOPHENYL)MORPHOLIN-3-ONE is used in the preparation of various Morpholine based pharmaceuticals.
Uses	Rivaroxaban intermediate
Flammability and Explosibility	Nonflammable

4-(4-AMINOPHENYL)MORPHOLIN-3-ONE Preparation Products And Raw materials

Raw materials

Sulfuric acid-->Dichloromethane-->Thionyl chloride-->Toluene-->Potassium carbonate-->Triethylamine-->Acetone-->Palladium-->Acetonitrile-->Sodium hydride-->1,4-Dioxane-->Chromium(VI) oxide-->4-Nitroaniline-->Ethyl chloroacetate-->Monoethanolamine-->STANNOUS CHLORIDE-->Benzyltriethylammonium chloride-->4-Fluoronitrobenzene-->2-(2-Chloroethoxy)ethanol

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