4-BROMO-BENZO[B]THIOPHENE
4-BROMO-BENZO[B]THIOPHENE
  • CAS No.:5118-13-8
Other grades of this product :
4-BROMO-BENZO[B]THIOPHENE Basic information
Synthesis
Product Name:4-BROMO-BENZO[B]THIOPHENE
Synonyms:4-BROMO-BENZO[B]THIOPHENE;4-Bromobenzothiophene;4-BROMO-1-BENZOTHIOPHENE;4-Bromothianaphthene;5-cyanobenzothiophene;4-bromo-thiophene;Benzo[b]thiophene,4-broMo-;4-Bromo-1-benzothiophene, 4-Bromothianaphthene
CAS:5118-13-8
MF:C8H5BrS
MW:213.09
EINECS:814-115-6
Product Categories:Benzothiophene;Halogenated;Organohalides
Mol File:5118-13-8.mol
4-BROMO-BENZO[B]THIOPHENE Chemical Properties
Boiling point 144 °C(Press: 20 Torr)
density 1.649±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
Safety Information
Hazard Codes Xi
Hazard Note Irritant
HS Code 2934999090
MSDS Information
4-BROMO-BENZO[B]THIOPHENE Usage And Synthesis
SynthesisThe traditional synthesis method is to take 2-bromo-6-fluorobenzaldehyde as a raw material, cyclize the raw material with mercaptoacetic acid in a DMF solvent to obtain 4-chlorobenzo [b] thiophene-2-carboxylic acid, and then decarboxylate the product at a high temperature in a quinoline/copper powder system to obtain the 4-chlorobenzo [b] thiophene. 
Uses4-bromobenzo [b] thiophene is an important intermediate in the drug ipiprazole for the treatment of schizophrenia.
4-BROMO-BENZO[B]THIOPHENE Preparation Products And Raw materials
Preparation Products6-BROMO-BENZO[B]THIOPHENE

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