N4-Benzoylcytosine

N4-Benzoylcytosine
  • CAS No.:26661-13-2
Other grades of this product :
N4-Benzoylcytosine Basic information
Product Name:N4-Benzoylcytosine
Synonyms:Benzamide, N-(2,3-dihydro-2-oxo-4-pyrimidinyl)-;N4-Benzoylcytosine;N4-Benzoylcytosine≥ 99% (HPLC);N-(2-Oxo-3H-pyrimidin-4-yl)benzamide;n-(2-oxo-1,2-dihydro-4-pyrimidinyl)benzamide;N4-BENZOYLCYTOSINE;LABOTEST-BB LT00138031;N-Benzoylcytosine
CAS:26661-13-2
MF:C11H9N3O2
MW:215.21
EINECS:628-907-2
Product Categories:Heterocyclic Compounds;Building Blocks;Heterocyclic Building Blocks;Pyrimidines
Mol File:26661-13-2.mol
N4-Benzoylcytosine Chemical Properties
Melting point >300 °C (dec.) (lit.)
density 1.33±0.1 g/cm3(Predicted)
vapor pressure 0Pa at 25℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Aqueous Acid (Slightly, Heated), DMSO+DCl (Slightly, Heated)
form Solid
pka7.75±0.10(Predicted)
color Off-White
InChIKeyXBDUZBHKKUFFRH-UHFFFAOYSA-N
Surface tension72.2mN/m at 1g/L and 21.2℃
CAS DataBase Reference26661-13-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 20/22-36/37/38
Safety Statements 26-36
WGK Germany 3
HS Code 29335990
MSDS Information
ProviderLanguage
SigmaAldrich English
N4-Benzoylcytosine Usage And Synthesis
Chemical PropertiesWhite or almost white crystalline powder
UsesN4-Benzoylcytosine may be employed for the following syntheses:
  • 3′-C-ethynyl and 3′-C-(1,4-disubstituted-1,2,3-triazolo) double-headed pyranonucleosides
  • 2′-C-methyl-4′-thiocytidine, via the Pummerer reaction
  • 2′-fluorinated L-nucleoside analogs
UsesN4-Benzoylcytosine is a reactant in the synthesis of 1'',2''-cyclopentyl nucleosides as potential antiviral agents.
General DescriptionN4-Benzoylcytosine is an amide and its anti-microbial activity against pathogenic microorganisms has been studied using the Disk Diffusion and the Pour Plate method. It can be synthesized via the condensation of benzoyl chloride with cytosine.

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