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| FMOC-O-tert-Butyl-L-serine Basic information |
| FMOC-O-tert-Butyl-L-serine Chemical Properties |
| Melting point | 130.5-135.5 °C(lit.) | | alpha | 25 º (c=1,EtOAc 24 ºC) | | Boiling point | 510.36°C (rough estimate) | | density | 1.2369 (rough estimate) | | refractive index | 24 ° (C=1, AcOEt) | | storage temp. | 2-8°C | | pka | 3.44±0.10(Predicted) | | form | powder to crystal | | color | White to Almost white | | optical activity | [α]20/D +25.5±1°, c = 1% in ethyl acetate | | BRN | 3632013 | | InChIKey | REITVGIIZHFVGU-IBGZPJMESA-N | | CAS DataBase Reference | 71989-33-8(CAS DataBase Reference) |
| FMOC-O-tert-Butyl-L-serine Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powde | | Uses | Fmoc-Ser(tBu)-OH is an N-terminal protected reagent used in the peptide synthesis. Some of the reported examples are:- Total synthesis of an antibiotic, daptomycin, by cyclization via a chemoselective serine ligation.
- Preparation of MUC1, a T-cell helper peptide, using iterative pentafluorophenyl ester-mediated fragment condensations.
- Linear solid-phase peptide synthesis of ubiquitin and diubiquitin.
| | General Description | The product number for this product was previously 04-12-1033.To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”. |
| FMOC-O-tert-Butyl-L-serine Preparation Products And Raw materials |
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