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| TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE Basic information | | Reactions |
| TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE Chemical Properties |
| Melting point | 164 °C(lit.) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Dichloromethane (Slightly), Methanol (Slightly) | | form | Powder | | color | White | | Water Solubility | Soluble in water. | | InChIKey | KZGFMSRKDNYVKL-UHFFFAOYSA-N |
| Risk Statements | 36/37/38 | | Safety Statements | 22-24/25 | | RIDADR | 1759 | | WGK Germany | 3 | | TSCA | No | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29209090 |
| TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE Usage And Synthesis |
| Reactions | Non-pyrophoric, air-stable derivative suitable as a replacement for the neat phosphine in a variety of stoichiometric and catalytic processes.
| | Chemical Properties | White powder | | Uses | suzuki reaction | | Uses | Tricyclohexylphosphonium Tetrafluoroborate acts as a reagent in the synthesis of potent JAK2 inhibitor BMS-911543 as a potential treatment for myeloproliferative disorders, preparation of Lapatinib intermediate via arylation of furfural with bromochlorofluorobenzyloxyphenylquinazolinamine, structure-activity relationships of carboline and carbazole derivatives as ATP-competitive kinesin spindle protein inhibitors. | | Uses | Tricyclohexylphosphine tetrafluoroborate may be used in the following processes:- As a ligand for preparing C-homoaporphine alkaloids via microwave-assisted direct-arylation.
- To synthesize poly-[9,9-bis(3-propylamide-2-methylpropyl sulfonic acid) fluorene]-co-(4,4′-diphenyl) (PFDBSO3H), which can be employed as a template and doping agent for enhancing the conductivity of poly(3,4-ethylenedioxythiophene) (PEDOT) films.
- To improve the reactivity of palladium-catalyzed Suzuki-Miyaura cross-coupling reaction between MIDA boronates and less activated alkenyl tosylates.
| | General Description | Tricyclohexylphosphine tetrafluoroborate (PCy3·HBF4) is an inexpensive and air-stable phosphine ligand, commonly used in cross-coupling reactions. |
| TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE Preparation Products And Raw materials |
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