L-Prolinamide

CAS No.：7531-52-4

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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L-Prolinamide Basic information

Product Name:	L-Prolinamide
Synonyms:	PROLINE-NH2;PROLINAMIDE;(S)-PYRROLIDINE-2-CARBOXYLIC ACID AMIDE;(S)-PROLINAMIDE;H-PRO-NH2;L-PROLINE AMIDE;L-(-)-PROLINAMIDE;L-PROLINAMIDE
CAS:	7531-52-4
MF:	C5H10N2O
MW:	114.15
EINECS:	231-397-0
Product Categories:	APIs;Amino Acids;Proline [Pro, P];Amino Acid Derivatives;Peptide Synthesis;Proline;Amino Acids and Derivatives;Amides (Chiral);Chiral Building Blocks;Synthetic Organic Chemistry;Miscellaneous Reagents;Aromatics;Catalyst;Heterocycles;AMINOACIDS DERIVATIVES;API;Pharmaceuticalintermediates;7531-52-4
Mol File:	7531-52-4.mol

L-Prolinamide Chemical Properties

Melting point	95-97 °C (lit.)
alpha	-106 º (c=2, EtOH)
Boiling point	213.66°C (rough estimate)
density	1.1008 (rough estimate)
refractive index	1.4720 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	16.21±0.20(Predicted)
form	Powder or Granules
color	White to straw
optical activity	[α]20/D 106°, c = 2 in ethanol
Water Solubility	Soluble in water and ethanol (50 mg/ml).
BRN	80807
InChIKey	VLJNHYLEOZPXFW-BYPYZUCNSA-N
CAS DataBase Reference	7531-52-4(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn
Risk Statements	22-36/37/38
Safety Statements	22-24/25-36/37/39-26
WGK Germany	3
F	10
HS Code	29339900

MSDS Information

Provider	Language
L-Prolinamide	English
SigmaAldrich	English
ACROS	English
ALFA	English

L-Prolinamide Usage And Synthesis

Chemical Properties	Crystalline
Uses	Proline based organocatalyst.
Uses	It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. Also it is a efficient organocatalysts for aldol reactions on water.
Definition	ChEBI: The carboxamide derivative of L-proline.

L-Prolinamide Preparation Products And Raw materials

Preparation Products

2-Pyrrolidinecarboxamide,1-(hydroxyacetyl)-,(S)-(9CI)-->Z-PRO-NH2-->D-1-N-Boc-prolinamide-->Pyrrolidine, 2-(methylaminomethyl)-

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