Product

3-AMINOPROPIONITRILE FUMARATE

CAS No.：2079-89-2

Other grades of this product :

3-AMINOPROPIONITRILE FUMARATE Basic information

Product Name:	3-AMINOPROPIONITRILE FUMARATE
Synonyms:	2-Cyanoethylamine hemifumarate;3-Aminopionitrile Fumarate;B-aminopropionitrile monofumarate;di(2-cyanoethylammonium) fumarate;3-AMINOPROPIONITRILE FUMARATE, 99+%;bis(3-aminopropiononitrile) fumarate;3-Aminopropionitrile fumarate, 98+%;3-AMINOPROPIONITRILE FUMARATE (BETA-) 98+%
CAS:	2079-89-2
MF:	C7H10N2O4
MW:	186.17
EINECS:	218-208-7
Product Categories:	Building Blocks;C1 to C5;Lysyl oxidase;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;C1 to C5;Cyanides/Nitriles;Nitrogen Compounds;Enzyme Inhibitors by Enzyme;L to;Inhibitors
Mol File:	2079-89-2.mol

3-AMINOPROPIONITRILE FUMARATE Chemical Properties

Melting point	177 °C (dec.)(lit.)
storage temp.	-20°C
form	Crystalline Powder
color	White
Water Solubility	almost transparency
BRN	3573532
CAS DataBase Reference	2079-89-2(CAS DataBase Reference)
EPA Substance Registry System	Propanenitrile, 3-amino-, (2E)-2-butenedioate (2:1) (2079-89-2)

Safety Information

Hazard Codes	T
Risk Statements	61
Safety Statements	53-45
WGK Germany	3
RTECS	UG0700000
TSCA	Yes
HS Code	29269095
Toxicity	LDLo orl-rat: 800 mg/kg TJADAB 5,33,72

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

3-AMINOPROPIONITRILE FUMARATE Usage And Synthesis

Chemical Properties	WHITE CRYSTALLINE POWDER
Uses	3-Aminopropionitrile fumarate salt has been used as a lysyl oxidase (LOX) inhibitor: to inhibit collagen cross-linking during microtissue formation and culture in LIM domain only 1 (LMO1)- or vector-expressing BE2C neuroblastoma cell line in transwell migration and invasion assay in lysyl oxidase (LOX) activity assay to study requirement of LOX activity for inducing hypoxia-inducible factor (HIF)2A-dependent stiffness in mouse organoids
Definition	ChEBI: A fumarate salt prepared from beta-aminopropionitrile by reaction of one molecule of fumaric acid for every two molecules of beta-aminopropionitrile.
Biochem/physiol Actions	3-Aminopropionitrile (β-Aminopropionitrile (BAPN)) functions as an irreversible inhibitor of lysyl oxidase (LOX), an enzyme involved in collagen cross-linking.
Safety Profile	Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NO, and CN-. See also NITRILES.

3-AMINOPROPIONITRILE FUMARATE Preparation Products And Raw materials

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