Piperidine hydrochloride
Piperidine hydrochloride
  • CAS No.:6091-44-7
Other grades of this product :
Piperidine hydrochloride Basic information
Product Name:Piperidine hydrochloride
Synonyms:hexahydropyridinehydrochloride;PIPERIDINE HYDROCHLORIDE;PIPERIDINIUM CHLORIDE;PIPERIDINIUM HYDROCHLORIDE;PIPERIDINE HYDROCHLORIDE, CRYSTALLIZED;PIPERIDINE HCL;Piperidinehydrochloride,99%;Piperidiniumchlorid
CAS:6091-44-7
MF:C5H12ClN
MW:121.61
EINECS:228-033-8
Product Categories:Piperidine;Building Blocks;Heterocyclic Building Blocks;Piperidines
Mol File:6091-44-7.mol
Piperidine hydrochloride Chemical Properties
Melting point 245-248 °C(lit.)
Boiling point 347.05℃
density 1,12 g/cm3
vapor density 2.94 (vs air)
vapor pressure 63.6 mm Hg ( 37.8 °C)
Fp >230 °F
storage temp. Store below +30°C.
solubility >1500g/l
form Solid:crystalline
PH6-8 (111g/l, H2O, 20℃)
Water Solubility soluble
Sensitive Hygroscopic
BRN 3611699
InChIKeyVEIWYFRREFUNRC-UHFFFAOYSA-N
LogP-1.92
CAS DataBase Reference6091-44-7(CAS DataBase Reference)
EPA Substance Registry SystemPiperidine hydrochloride (6091-44-7)
Safety Information
Hazard Codes T
Risk Statements 25-37-36/37/38-23/24/25
Safety Statements 36/37/39-45-28A-26
RIDADR UN 2811 6.1/PG 3
WGK Germany 1
RTECS TN0400000
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29333200
MSDS Information
ProviderLanguage
Piperidine hydrochloride English
ACROS English
SigmaAldrich English
ALFA English
Piperidine hydrochloride Usage And Synthesis
Chemical PropertiesWHITE FINE CRYSTALLINE POWDER
UsesPiperidine hydrochloride is used an intermediate in the manufacture of active pharmaceutical ingredients like anti Parkinsonan agent Biperiden; anti depressant agent Clocapramine hydrochloride and muscle relaxant tolperisone.
UsesReagent for synthesis of:
  • Quinoline selenium compounds
  • Peripheral seratonin 5-HT3 receptor ligands
Reactant for synthesis of phthalazinone derivatives as topically active phosphodiesterase 4 inhibitorsReactant for:
  • Mannich reactions
  • Asymmetric hydrogenation of quinolines
  • Chemoselective reductive amination of carbonyl compounds
Purification MethodsCrystallise the salt from EtOH/diethyl ether in the presence of a small amount of HCl. [Beilstein 20 H 6, 20 II 10, 20 III/IV 295, 20/2 V 13.]
Piperidine hydrochloride Preparation Products And Raw materials
Preparation ProductsPiperidine-->Befunolol-->Bipariden-->3-(1-Piperidinyl)propiophenone HCl-->Diisopropylamine hydrochloride-->2-OXOBUTANALDEHYDE

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