D-(-)-Arginine hydrochloride

CAS No.：627-75-8

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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D-(-)-Arginine hydrochloride Basic information

Product Name:	D-(-)-Arginine hydrochloride
Synonyms:	monohydrochloride,d-arginin;H-D-ARG-OH HCL;D-2-AMINO-5-GUANIDINOVALERIC ACID HYDROCHLORIDE;D-ARGININE HCL;D(-)-ARGININE HYDROCHLORIDE;D-ARGININE HYDROCHLORIDE;D-ARGININE MONOHYDROCHLORIDE;D-Arginine.monohydrchloride
CAS:	627-75-8
MF:	C6H15ClN4O2
MW:	210.66
EINECS:	211-010-1
Product Categories:	Peptide Synthesis;AMINO ACIDS;Arginine Metabolism;ArginineNitric Oxide and Cell Stress;Amino Acid Derivatives;Nitric Oxide Metabolism
Mol File:	627-75-8.mol

D-(-)-Arginine hydrochloride Chemical Properties

Melting point	216-218 °C(lit.)
alpha	-21 º (c=3.5 1 N HCl)
storage temp.	Inert atmosphere,Room Temperature
Water Solubility	Soluble in water (50 mg/ml), and 3N HCl (5).
BRN	5773432
InChIKey	KWTQSFXGGICVPE-PGMHMLKASA-N
CAS DataBase Reference	627-75-8(CAS DataBase Reference)
NIST Chemistry Reference	Arginine hydrochloride(L)(627-75-8)
EPA Substance Registry System	D-Arginine, monohydrochloride (627-75-8)

Safety Information

Risk Statements	20/22
Safety Statements	22-24/25
WGK Germany	3
RTECS	CF1995000
TSCA	Yes
HS Code	29252900
Toxicity	LD50 ipr-rat: 3582 mg/kg ABBIA4 64,319,56

MSDS Information

Provider	Language
D-(-)-Arginine hydrochloride	English
ACROS	English
SigmaAldrich	English
ALFA	English

D-(-)-Arginine hydrochloride Usage And Synthesis

Chemical Properties	WHITE CRYSTALLINE POWDER
Uses	The influence in creatinine metabolismis that by that d-arginine monohydrochloride caused slightly larger increases in muscle creatine. D-Arginyl ethyl ester was synthesized by vigorously stirring D-arginine monohydrochloride and excess anhydrous ethanol in an ice bath.
Uses	D-arginine attenuates increased arginase expression, oxidative stress, endothelial dysfunction, and advanced glycation endproducts formation induced by methylgloxyl and high glucose. This attenuation by D-arginine is thought to occur through an endothelial NOS independent mechanism.
Safety Profile	Moderately toxic byintraperitoneal route. When heated to decomposition itemits toxic vapors of NOx, HCl, and Cl^-.

D-(-)-Arginine hydrochloride Preparation Products And Raw materials

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