Ufiprazole
Ufiprazole
  • CAS No.:73590-85-9
Other grades of this product :

Ufiprazole Basic information
Synthesis
Product Name:Ufiprazole
Synonyms:5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL THIO-1H-BENZIMIDAZOLE;5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYLMERCAPTOBENZIMIDAZOLE;5-METHOXY-2-[[(3,5-DIMETHYL-4-METHOXY PYRIDINYL)-METHYL]THIO]-1H-BENZIMIDAZOLE;2-[(4-METHOXYETHOXY-3,5-DIMETHYL-2-PYRIDINYL)-METHYLTHIO]-5-METHOXYBENZIMIDAZOLE;2-{[(3,5-dimethyl-4-methoxy-2-pyridinyl)-methyl]-thio}-5-methoxy-1h-benzimidazole;OMEPRAZOLE SULPHIDE;H 168/22;ufiprazole
CAS:73590-85-9
MF:C17H19N3O2S
MW:329.42
EINECS:615-997-3
Product Categories:zjh;Inhibitors;(intermediate of lamivudine);Intermediates & Fine Chemicals;Metabolites;Pharmaceuticals;Various Metabolites and Impurities
Mol File:73590-85-9.mol
Ufiprazole Chemical Properties
Melting point 122.0 to 126.0 °C
Boiling point 539.7±60.0 °C(Predicted)
density 1.28±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka9.81±0.10(Predicted)
form Solid
color White to Off-White
λmax307nm(MeOH)(lit.)
InChIKeyXURCIPRUUASYLR-UHFFFAOYSA-N
CAS DataBase Reference73590-85-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
WGK Germany 3
HS Code 29339900
MSDS Information
Ufiprazole Usage And Synthesis
SynthesisUfiprazole can be synthesized by the condensation reaction of 2-mercapto-5-methoxybenzimidazole and 2-chloromethyl-4-methoxy-3,5-lutidine.
DescriptionOmeprazole sulfide is an intermediate used in the production of the gastric proton pump inhibitors, omeprazole and esomeprazole . As a degradation product, it is reported to be a direct-acting inhibitor of cytochrome P450 2C19 in pooled human liver microsomes (IC50 = 9.7 μM).
UsesA metabolite of Omeprazole
UsesOmeprazole Sulfide (Esomeprazol EP Impurity C(Omeprazole EP Impurity C)) is a metabolite of Omeprazole.
Biological ActivityUfiprazole (Omeprazole sulfide) is an intermediate in the production of gastric proton pump inhibitors omeprazole and esomeprazole.
Ufiprazole Preparation Products And Raw materials
Raw materials2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
Preparation ProductsOMEPRAZOLE

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