Cyclobutanemethanol

Cyclobutanemethanol
  • CAS No.:4415-82-1

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
Cyclobutanemethanol Basic information
Product Name:Cyclobutanemethanol
Synonyms:(HYDROXYMETHYL)CYCLOBUTANE;cyclobutylcarbinol;CYCLOBUTYLMETHANOL;CYCLOBUTANECARBINOL;CYCLOBUTANEMETHANOL;RARECHEM AK ML 0579;Cyclobutanemethanol,99%;Cyclobutylcarbinol~Hydroxymethylcyclobutane
CAS:4415-82-1
MF:C5H10O
MW:86.13
EINECS:224-575-4
Product Categories:Benazir bhutto, Nadine brown brown, analgesic, such as intermediates.;API intermediates;Cyclobutanes & Cyclobutenes;Simple 4-Membered Ring Compounds;Cycloalkanes;Alcohols;C2 to C6;Oxygen Compounds
Mol File:4415-82-1.mol
Cyclobutanemethanol Chemical Properties
Melting point 68.5 °C
Boiling point 143-144 °C(lit.)
density 0.913 g/mL at 25 °C(lit.)
refractive index n20/D 1.446(lit.)
Fp 104 °F
storage temp. Sealed in dry,2-8°C
pka15.26±0.10(Predicted)
form Liquid
color Clear colorless
Water Solubility immiscible
BRN 2036027
InChIKeyWPOPOPFNZYPKAV-UHFFFAOYSA-N
CAS DataBase Reference4415-82-1(CAS DataBase Reference)
NIST Chemistry ReferenceCyclobutanemethanol(4415-82-1)
Safety Information
Risk Statements 10
Safety Statements 16-24/25
RIDADR UN 1987 3/PG 3
WGK Germany 3
HazardClass 3
PackingGroup III
HS Code 29061900
MSDS Information
ProviderLanguage
Hydroxymethylcyclobutane English
SigmaAldrich English
ACROS English
ALFA English
Cyclobutanemethanol Usage And Synthesis
Chemical PropertiesColorless to Almost colorless clear liquid.
UsesCyclobutanemethanol was used in the synthesis of bicyclic lactone.
ApplicationCyclobutanemethanol is a drug used to treat inflammatory diseases. It is an uptake inhibitor that blocks the transport of uridine into cells, preventing the activation of G-protein coupled receptors and the subsequent production of inflammatory mediators. Cyclobutanemethanol has been shown to have anti-inflammatory properties by inhibiting the CB2 receptor, which is found in large quantities in inflammatory tissues. It also prevents dehydration and increases blood flow to inflamed areas by acting on vascular endothelial cells. It has been shown to inhibit influenza virus replication in vitro, but not in vivo.
General DescriptionOxidation of cyclobutanemethanol in the presence of lead tetraacetate and lead tetraacetate/metal chloride has been investigated.
SynthesisCyclobutanemethanol can be synthesized from two molecules of hydrochloric acid and one molecule of cyclobutane. The synthesis pathway includes removal of a hydroxy group and addition of an alkynyl group via hydrogen bonding interactions with chloride ions.

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