5-Chloro-1,3-dimethoxybenzene

5-Chloro-1,3-dimethoxybenzene
  • CAS No.:7051-16-3
Other grades of this product :
5-Chloro-1,3-dimethoxybenzene Basic information
Product Name:5-Chloro-1,3-dimethoxybenzene
Synonyms:1-chloro-3,5-dimethoxy-benzen;Phloroglucinol Impurity 35;3,5-dimethoxychlorobenzene;5-CHLORORESORCINOL DIMETHYL ETHER;5-CHLORO-1,3-DIMETHOXYBENZENE;1-CHLORO-3,5-DIMETHOXYBENZENE;NCS 220095;5-Ch
CAS:7051-16-3
MF:C8H9ClO2
MW:172.61
EINECS:230-330-2
Product Categories:Aromatic Hydrocarbons (substituted) & Derivatives;Anisoles, Alkyloxy Compounds & Phenylacetates;Chlorine Compounds;Building Blocks for Dendrimers;Functional Materials;Pharmaceutical Intermediate;Ethers;Organic Building Blocks;Oxygen Compounds
Mol File:7051-16-3.mol
5-Chloro-1,3-dimethoxybenzene Chemical Properties
Melting point 34-36 °C (lit.)
Boiling point 82-83°C 0,6mm
density 1.1910 (rough estimate)
refractive index 1.5100 (estimate)
Fp 234 °F
storage temp. Sealed in dry,Room Temperature
solubility almost transparency in Methanol
form Crystalline Powder
color White to yellow or pink
BRN 2327304
InChIKeyWQHNWJBSROXROL-UHFFFAOYSA-N
CAS DataBase Reference7051-16-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39
WGK Germany 3
RTECS CZ0320000
Hazard Note Irritant
HS Code 29093090
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
5-Chloro-1,3-dimethoxybenzene Usage And Synthesis
Description5-Chloroesorcinol dimethyl ether is a synthetic intermediate useful for pharmaceutical synthesis.
Chemical PropertiesWhite to yellow or pink crystalline powder
Uses5-Chloro-1,3-dimethoxybenzene was used in the regioselective synthesis of TMC-264, tricyclic structure having chloro-1H-dibenzo[b,d]pyran-4,6-dione skeleton.
General Description5-Chloro-1,3-dimethoxybenzene participates in Suzuki-Miyaura cross-coupling reactions of aryl- and heteroaryl chlorides with potassium cyclobutyltrifluoroborate.
5-Chloro-1,3-dimethoxybenzene Preparation Products And Raw materials
Preparation Products3,5-Dimethoxytoluene-->3,5-Dichlorophenol-->3,5-Dimethoxybenzylamine

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