Product

(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane

CAS No.：119302-24-8

Other grades of this product :

(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane Basic information

Product Name:	(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane
Synonyms:	2-β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5a-androstan-3a,17β-diol-17-acetate;(2B,3A,5A,16B,17B)-17-ACETOXY-3-HYDROXY-2-(4-MORPHOLINYL)-16-(1-PYRROLIDINYL)ANDROSTANE;（2，3，5，16，17）-17-acetoxy-3-hydroxy-2-（4-morpholinyl）-16-（1-pyrrolidinyl）androstane;(2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)-androstane-3,17-diol 17-acetate;2β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5α-androstane-3α,17β-diol 17-acetate;2beta-(4-Morpholinyl)-16beta-(1-pyrrolidinyl)-5alpha-androstane-3alpha,17beta-diol 17-acetate;(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane (2b,3a,5a,16b,17b)-1;RocuroniuM BroMide InterMediate VIII
CAS:	119302-24-8
MF:	C29H48N2O4
MW:	488.7
EINECS:	601-596-0
Product Categories:	Intermediates
Mol File:	119302-24-8.mol

(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane Chemical Properties

Melting point	152-156°C
Boiling point	574.1±50.0 °C(Predicted)
density	1.17
vapor pressure	0Pa at 25℃
storage temp.	2-8°C
solubility	Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
form	Solid
pka	14.85±0.70(Predicted)
color	White to Light Brown
LogP	3.9 at 22℃ and pH12

Safety Information

MSDS Information

(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane Usage And Synthesis

Uses	(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane is used in the synthesis of the neuromuscular blocking agent rocuronium bromide.

(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane Preparation Products And Raw materials

Raw materials

(2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol-->1-Acetylimidazole-->17-Desacetyl Rocuronium Bromide-->4-NITROPHENYL ACETATE-->Androstane-3,17-diol,2-(4-morpholinyl)-16-(1-pyrrolidinyl)-->Acetyl chloride

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