Product

DL-Tryptophan

CAS No.：54-12-6

Other grades of this product :

DL-Tryptophan Basic information

Product Name:	DL-Tryptophan
Synonyms:	(rs)-tryptophan;2-Amino-3,3’-IndolylpropanoicAcid;DL-Trytophan;DL-Trytophane;DL-TRYPTOPHAN extrapure CHR;(±)-α-Amino-3-indolepropionic acid, (±)-2-Amino-3-(3-indolyl)propionic acid, DL-3β-Indolylalanine;α-amino-β-indolepropinic acid;DL-Tryptoplaan
CAS:	54-12-6
MF:	C11H12N2O2
MW:	204.23
EINECS:	200-194-9
Product Categories:	Amino Acids & Derivatives;Tryptophan [Trp, W];alpha-Amino Acids;Amino Acids;Biochemistry;Indoles;Amino Acids Derivatives;Tryptophans;Amino Acids;Alphabetical Listings;Stable Isotopes
Mol File:	54-12-6.mol

DL-Tryptophan Chemical Properties

Melting point	289-290 °C (dec.)(lit.)
Boiling point	342.72°C (rough estimate)
alpha	[α]D20 -1～1°(c=1, dil. HCl)
density	1.1754 (rough estimate)
refractive index	1.5200 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	methanol: water (7:3): soluble
form	Powder
pka	2.30±0.10(Predicted)
color	White to light beige or light yellow
Odor	Odorless
Water Solubility	10 g/L (20 ºC)
BRN	86196
Stability:	Stable. Incompatible with strong oxidizing agents, strong acids.
InChIKey	QIVBCDIJIAJPQS-UHFFFAOYSA-N
CAS DataBase Reference	54-12-6(CAS DataBase Reference)
NIST Chemistry Reference	Tryptophane(54-12-6)
EPA Substance Registry System	Tryptophan (54-12-6)

Safety Information

Hazard Codes	Xi
Risk Statements	22-36/37/38-37/38-41
Safety Statements	24/25-36/37/39-36-26
WGK Germany	1
RTECS	YN6129200
F	8
TSCA	Yes
HS Code	29339990

MSDS Information

Provider	Language
DL-Tryptophan	English

DL-Tryptophan Usage And Synthesis

Chemical Properties	White crystals. Slightly soluble in water; stable in alkaline solution; decomposed by strong acids.
Uses	An amino acid precursor of serotonin and melatonin.
Uses	DL-Tryptophan is an amino acid precursor of serotonin and melatonin. It is a dietary supplement for use as an antidepressant, anxiolytic, and sleep aid. DL-tryptophan also can be used as feed nutrition enhancer, antioxidants.
Definition	ChEBI: An alpha-amino acid that is alanine bearing an indol-3-yl substituent at position 3.
General Description	Tryptophan is the precursor for 5-hydroxy-tryptamin and an essential α-amino acid. DL-Tryptophan exists as a zwitterion during crystallization.
Biochem/physiol Actions	DL-Tryptophan binding to bovine serum albumin is employed for its affinity based chromatographic purification. Supplementation of tryptophan in diets of rat induce bladder tumor.
Safety Profile	Experimental reproductive effects. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits toxic fumes of NOx.

DL-Tryptophan Preparation Products And Raw materials

Raw materials

Acetic acid-->Sodium sulfate-->Acetic anhydride-->Water-->Dimethylamine-->Acrolein-->Starch-->Pyruvic acid-->Sulfurous Acid-->formaldehyde-->Indole-->L-Alanine-->L-Phenylalanine-->1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester-->Inosine-->L-Tyrosine-->L-Tryptophan-->DL-Serine-->2-Methylindole-->N-[(tert-Butoxy)carbonyl]-D-tryptophan-->Gramine-->INDOPHENOL-->2-Acetamidoacrylic acid-->Pyridoxal 5'-phosphate monohydrate-->AMINOMALONIC ACID

Preparation Products

L-Tryptophan-->D(+)-Tryptophan

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