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| Product Name: | Marbofloxacin | | Synonyms: | 7h-pyrido(3,2,1-ij)(4,1,2)benzoxadiazine-6-carboxylicacid,2,3-dihydro-9-fluor;o-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-;MARBOFLOXACIN;Marbofloxacin, >=99%;Marbofloxacin Solution, 1000ppm;Marbofloxacin Solution, 100ppm;CS-939;9-FLUORO-2,3-DIHYDRO-3-METHYL-10-(4-METHYL-PIPERAZINO)-7-OXO-7H-PYRIDO[1,2,3-IJ][1,2,4]BENZOXADIAZINE-6-CARBOXYLIC ACID | | CAS: | 115550-35-1 | | MF: | C17H19FN4O4 | | MW: | 362.36 | | EINECS: | 640-416-5 | | Product Categories: | API;Active Pharmaceutical Ingredients;Aromatics Compounds;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 115550-35-1.mol |
| Marbofloxacin Chemical Properties |
| Melting point | 268-269°C (dec.) | | Boiling point | 571℃ | | density | 1.55±0.1 g/cm3(Predicted) | | Fp | >110°(230°F) | | storage temp. | Inert atmosphere,2-8°C | | solubility | Chloroform (Slightly, Heated) | | form | neat | | pka | 6.02±0.20(Predicted) | | color | Light Yellow | | Water Solubility | Soluble in DMSO at 2mg/ml. Soluble in water or ethanol at <1mg/ml | | Merck | 14,5750 | | InChIKey | BPFYOAJNDMUVBL-UHFFFAOYSA-N | | CAS DataBase Reference | 115550-35-1(CAS DataBase Reference) |
| Marbofloxacin Usage And Synthesis |
| Brand Name(s) in US | Zeniquin, Marbocyl
| | Description | Marbofloxacin is a fluoroquinolone antibiotic that is active against P. multocida in vitro (MIC = 0.016 μg/ml). It exhibits broad-spectrum antibacterial activity mediated by the inhibition of DNA gyrase, with MIC values ranging from 0.016 to 0.4 and 0.19 to 1.7 μg/ml against various Gram-negative and Gram-positive bacterial isolates, respectively. In vivo, the administration of marbofloxacin (2 mg/kg, i.m.) after infection prevents the formation of pulmonary lesions in a bovine calf model of M. haemolytica A1 pneumonia. Oral marbofloxacin (2 mg/kg per day) also exhibits antileishmanial activity in a canine model of leishmaniasis, decreasing parasitic load by 72%. Formulations containing marbofloxacin have been used in the veterinary treatment of bacterial infections. | | Chemical Properties | Crystalline Solid | | Uses | Fluorinated quinolone antibacterial | | Uses | A broad spectrum antibiotic commonly used to target Pseudomonas and Staphylococci species | | Definition | ChEBI: A fluoroquinolone antibiotic that is 7-oxo-2,3-dihydro-7H-[1,3,4]oxadiazino[6,5,4-ij]quinoline substituted at positions 6, 9 and 10 by carboxy, fluoro and 4-methylpiperazin-1-yl groups, respectively. A synthetic, broad spect
um bactericidal agent, it is used in veterinary medicine, although its mechanism of action is not thoroughly understood. | | Veterinary Drugs and Treatments | Marbofloxacin is labeled for the treatment of susceptible bacterial
infections in dogs and cats. |
| Marbofloxacin Preparation Products And Raw materials |
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