4-Methylphenylsulfonylurea

4-Methylphenylsulfonylurea
  • CAS No.:1694-06-0
Other grades of this product :
4-Methylphenylsulfonylurea Basic information
Product Name:4-Methylphenylsulfonylurea
Synonyms:4-tolylsulfonylurea;N-(p-Toluenesulfonyl)urea;BenzenesulfonaMide,N-(aMinocarbonyl)-4-Methyl-;4-TOLUENSULFONYLUREA;Para-Toluene Sulfonyl Urea;Tolbutamide EP Impurity B;Gliclazide Impurity 12;N-(Aminocarbonyl)-4-methylbenzensulfona-mide
CAS:1694-06-0
MF:C8H10N2O3S
MW:214.24
EINECS:216-900-3
Product Categories:chemical additive;pharmaceutical intermediate
Mol File:1694-06-0.mol
4-Methylphenylsulfonylurea Chemical Properties
Melting point 196-198 °C
density 1.3844 (rough estimate)
refractive index 1.5690 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka5.07±0.10(Predicted)
form Solid
color White to Off-White
Water Solubility 777.9mg/L(37 ºC)
CAS DataBase Reference1694-06-0(CAS DataBase Reference)
Safety Information
Hazard Codes C
Risk Statements 34
Safety Statements 45-36/37/39-26
MSDS Information
ProviderLanguage
ACROS English
4-Methylphenylsulfonylurea Usage And Synthesis
Chemical Propertieswhite crystalline powder
Uses4-Methylphenylsulfonylurea can be used as pharmaceutical intermediate.
Uses4-Methylphenylsulfonylurea is used in the synthesis of Glyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic agent.
UsesN-(p-Toluenesulfonyl)urea is used in the synthesis of Glyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic agent.

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