(R)-3-(Boc-Amino)piperidine

CAS No.：309956-78-3

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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(R)-3-(Boc-Amino)piperidine Basic information

Solubility in organics Uses Uses storage

Product Name:	(R)-3-(Boc-Amino)piperidine
Synonyms:	CARBAMIC ACID, (3R)-3-PIPERIDINYL-, 1,1-DIMETHYLETHYL ESTER;(R)-TERT-BUTYL-PIPERIDINE-3-YICARBAMATE;(R)-PIPERIDIN-3-YL-CARBAMIC ACID TERT-BUTYL ESTER;(R)-3-AMINO-N-TBOC-PIPERIDINE;tert-Butyl [(3R)-piperidin-3-yl]carbamate, (3R)-3-[(tert-Butoxycarbonyl)amino]piperidine;Linagliptin interMediate B;Alogliptin Benzoate interMediate F;(R)-3-(Boc-amino)piperidine,97%
CAS:	309956-78-3
MF:	C10H20N2O2
MW:	200.28
EINECS:	685-989-2
Product Categories:	Piperidine Series;N-BOC;pharmacetical;Piperidine;Piperidines;Intermediates
Mol File:	309956-78-3.mol

(R)-3-(Boc-Amino)piperidine Chemical Properties

Melting point	121.0 to 125.0 °C
Boiling point	304.8±31.0 °C(Predicted)
density	1.02±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Soluble in methanol and ethanol.
pka	12.37±0.20(Predicted)
form	Solid
color	White to Off-White
optical activity	[α]22/D +3.2°, c = 0.5 in DMF
BRN	10662518
InChIKey	WUOQXNWMYLFAHT-MRVPVSSYSA-N
CAS DataBase Reference	309956-78-3(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,N
Risk Statements	37/38-41-50
Safety Statements	26-39-61-29-36
RIDADR	3077
WGK Germany	2
HazardClass	9
PackingGroup	Ⅲ
HS Code	29333990

MSDS Information

(R)-3-(Boc-Amino)piperidine Usage And Synthesis

Solubility in organics	Soluble in methanol and ethanol.
Uses	(R)-3-(Boc-amino)piperidine is used as an organic chemical synthesis intermediate.
Uses	(R)-3-(Boc-amino)piperidine is Boc protected (R)-3-Aminopiperidine (A627920, Dihydrochloride salt) which has been used as a reactant for the preparation of dipeptidyl peptidase IV inhibitors derived from Alogliptin.
storage	Stable under recommended storage conditions. Incompatible with oxidizing agents.
Chemical Properties	White powder
Uses	(R)-3-(Boc-amino)piperidine is used as an organic chemical synthesis intermediate.

(R)-3-(Boc-Amino)piperidine Preparation Products And Raw materials

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