(R)-3-(Boc-Amino)piperidine

(R)-3-(Boc-Amino)piperidine
  • CAS No.:309956-78-3
Other grades of this product :
(R)-3-(Boc-Amino)piperidine Basic information
Solubility in organics Uses Uses storage
Product Name:(R)-3-(Boc-Amino)piperidine
Synonyms:CARBAMIC ACID, (3R)-3-PIPERIDINYL-, 1,1-DIMETHYLETHYL ESTER;(R)-TERT-BUTYL-PIPERIDINE-3-YICARBAMATE;(R)-PIPERIDIN-3-YL-CARBAMIC ACID TERT-BUTYL ESTER;(R)-3-AMINO-N-TBOC-PIPERIDINE;tert-Butyl [(3R)-piperidin-3-yl]carbamate, (3R)-3-[(tert-Butoxycarbonyl)amino]piperidine;Linagliptin interMediate B;Alogliptin Benzoate interMediate F;(R)-3-(Boc-amino)piperidine,97%
CAS:309956-78-3
MF:C10H20N2O2
MW:200.28
EINECS:685-989-2
Product Categories:Piperidine Series;N-BOC;pharmacetical;Piperidine;Piperidines;Intermediates
Mol File:309956-78-3.mol
(R)-3-(Boc-Amino)piperidine Chemical Properties
Melting point 121.0 to 125.0 °C
Boiling point 304.8±31.0 °C(Predicted)
density 1.02±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Soluble in methanol and ethanol.
pka12.37±0.20(Predicted)
form Solid
color White to Off-White
optical activity[α]22/D +3.2°, c = 0.5 in DMF
BRN 10662518
InChIKeyWUOQXNWMYLFAHT-MRVPVSSYSA-N
CAS DataBase Reference309956-78-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,N
Risk Statements 37/38-41-50
Safety Statements 26-39-61-29-36
RIDADR 3077
WGK Germany 2
HazardClass 9
PackingGroup 
HS Code 29333990
MSDS Information
(R)-3-(Boc-Amino)piperidine Usage And Synthesis
Solubility in organics

Soluble in methanol and ethanol.

Uses

(R)-3-(Boc-amino)piperidine is used as an organic chemical synthesis intermediate.

Uses(R)-3-(Boc-amino)piperidine is Boc protected (R)-3-Aminopiperidine (A627920, Dihydrochloride salt) which has been used as a reactant for the preparation of dipeptidyl peptidase IV inhibitors derived from Alogliptin.
storage

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Chemical PropertiesWhite powder
Uses(R)-3-(Boc-amino)piperidine is used as an organic chemical synthesis intermediate.
(R)-3-(Boc-Amino)piperidine Preparation Products And Raw materials
Preparation Products(R)-3-Amino-1-methyl-piperidine

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