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| 4-AMINO-2-MERCAPTOPYRIMIDINE Basic information |
| 4-AMINO-2-MERCAPTOPYRIMIDINE Chemical Properties |
| Melting point | 285-290 °C (dec.)(lit.) | | Boiling point | 232.1±43.0 °C(Predicted) | | density | 1.313 (estimate) | | refractive index | 1.5800 (estimate) | | storage temp. | -20°C Freezer | | solubility | DMSO (Slightly), Water (Slightly) | | form | Powder | | pka | 7.91±0.10(Predicted) | | color | Yellow | | BRN | 112435 | | CAS DataBase Reference | 333-49-3(CAS DataBase Reference) | | EPA Substance Registry System | 2(1H)-Pyrimidinethione, 4-amino- (333-49-3) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | UW0520000 | | HS Code | 29335995 |
| 4-AMINO-2-MERCAPTOPYRIMIDINE Usage And Synthesis |
| Chemical Properties | Beige toYellow Powder | | Uses | This compound has been shown to inhibit iodothyronine 5’-deiodinase, the enzyme responsible for the 5’-deiodination of thyroxine in human liver cells. | | Uses | 2-Thiocytosine has been used to investigate the reactions involved in hole transfer (HT) in X-irradiated doped cytosine monohydrate. | | General Description | 2-Thiocytosine is a potential antileukemic and anticancer agent. 2-Thiocytosine in solid state has been investigated by (1)H-(14)N NMR-NQR double resonance (NQDR) spectroscopy and theoretically by the quantum theory of atoms in molecules (QTAIM)/density functional theory (DFT). | | Purification Methods | It is recrystallised from hot H2O and dried at 100o to constant weight. [Brown J Appl Chem (London) 9 203 1959, Russell et al. J Am Chem Soc 71 2279 1949.] It is used in transcription and translation studies [Rachwitz & Scheit Eur J Biochem 72 191 1977]. |
| 4-AMINO-2-MERCAPTOPYRIMIDINE Preparation Products And Raw materials |
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