| 1-(5-Fluoro-2-hydroxyphenyl)-1-ethanone Basic information |
| Product Name: | 1-(5-Fluoro-2-hydroxyphenyl)-1-ethanone |
| Synonyms: | 2-Acetyl-4-fluorophenol;1-(5-FLUORO-2-HYDROXY-P;5-Fluoro-2-hydroxyphenyl(methyl) ketone;5'-Fluoro-2'-hydroxyacetophenone,97%;JRH-01009, 1-(5-Fluoro-2-hydroxyphenyl)ethanone, 97%;5’-fluoro-2’-hydroxy-acetophenon;Ethanone, 1-(5-fluoro-2-hydroxyphenyl)-;5'-FLUORO-2'-HYDROXYACETOPHENONE |
| CAS: | 394-32-1 |
| MF: | C8H7FO2 |
| MW: | 154.14 |
| EINECS: | 206-893-5 |
| Product Categories: | Aryl Fluorinated Building Blocks;Building Blocks;C7 to C8;C7-C8;Chemical Synthesis;Fluorinated Building Blocks;Adehydes, Acetals & Ketones;Fluorine Compounds;Phenols;C7 to C8;Acetophenone series;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks;Alcohols and Derivatives;Carbonyl Compounds;Aromatic Acetophenones & Derivatives (substituted);ketone;(intermediate of nebivolol);Benzenes;Carbonyl Compounds;Ketones;1 |
| Mol File: | 394-32-1.mol |
| 1-(5-Fluoro-2-hydroxyphenyl)-1-ethanone Chemical Properties |
| Melting point | 56-58 °C(lit.) |
| Boiling point | 65-66 °C8 mm Hg(lit.) |
| density | 1.1850 (estimate) |
| Fp | 65-66°C/8mm |
| storage temp. | Inert atmosphere,Room Temperature |
| form | powder to crystal |
| pka | 10.17±0.18(Predicted) |
| color | White to Gray to Brown |
| Water Solubility | Soluble 0.68 G/L |
| BRN | 2359087 |
| CAS DataBase Reference | 394-32-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 5-Fluoro-2-hydroxyacetophenone(394-32-1) |
| Safety Information |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-22 |
| Safety Statements | 26-37/39-36/37/39 |
| WGK Germany | 3 |
| RTECS | AM8502300 |
| HazardClass | IRRITANT |
| HS Code | 29147000 |
| MSDS Information |
| Provider | Language |
|---|---|
| 1-(5-Fluoro-2-hydroxyphenyl)-1-ethanone | English |
| ACROS | English |
| SigmaAldrich | English |
| ALFA | English |
| 1-(5-Fluoro-2-hydroxyphenyl)-1-ethanone Usage And Synthesis |
| Chemical Properties | light yellow to beige-brown crystals or |
| Uses | 5′-Fluoro-2′-hydroxyacetophenone has been used in the preparation of:
|
| Preparation | Preparation by Fries rearrangement of 4-fluorophenyl acetate with aluminium chloride without solvent between 115° and 150° (88–89%). |
| 1-(5-Fluoro-2-hydroxyphenyl)-1-ethanone Preparation Products And Raw materials |
| Preparation Products | 2-chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone-->6-FLUOROCHROMONE |
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