Other grades of this product :
| tert-Butyl carbamate Basic information |
| Product Name: | tert-Butyl carbamate | | Synonyms: | tert-Butylcarbamate,98+%;tert-Butoxycarbonylamine;Carbamic Acid tert-Butyl EsterBoc-amide;tert-Butyl carbamate,Boc-amide;N-t-Butoxycarbonyl-amide(Boc-NH2);ert-Butyl carbamate;Boc-NH2 N-t-Butoxycarbonyl-aMide;tert-Butyl carbaMate 5GR | | CAS: | 4248-19-5 | | MF: | C5H11NO2 | | MW: | 117.15 | | EINECS: | 224-209-3 | | Product Categories: | Protected Amino Acids;pharmacetical | | Mol File: | 4248-19-5.mol |
| tert-Butyl carbamate Chemical Properties |
| Melting point | 105-108 °C (lit.) | | Boiling point | 218.95°C (rough estimate) | | density | 1.1274 (rough estimate) | | refractive index | 1.4206 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly), Methanol (Slightly) | | pka | 13.59±0.50(Predicted) | | form | Needles | | color | White to slightly yellow | | Water Solubility | Soluble in methylene chloride, chloroform, and alcohols. Slightly soluble in petroleum ether and water. | | BRN | 1744500 | | CAS DataBase Reference | 4248-19-5(CAS DataBase Reference) | | NIST Chemistry Reference | Tert-butyl carbamate(4248-19-5) |
| Hazard Codes | Xi | | Risk Statements | 36 | | Safety Statements | 39-26-24/25 | | WGK Germany | 3 | | HS Code | 29241990 |
| tert-Butyl carbamate Usage And Synthesis |
| Chemical Properties | White to slightly yellow needles | | Uses | tert-Butyl carbamate was used in palladium-catalyzed synthesis of N-Boc-protected anilines. It was used in the synthesis of tetrasubstituted pyrroles, functionalized with ester or ketone groups at C-3 position. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 28, p. 3421, 1963 DOI: 10.1021/jo01047a033 | | General Description | Palladium-catalyzed cross-coupling reaction of tert-butyl carbamate with various aryl(Het) halides with Cs2CO3 as base in 1,4-dioxane (solvent) has been investigated. |
| tert-Butyl carbamate Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye