2-Bromo-6-nitrophenol

CAS No.：13073-25-1

Other grades of this product :

2-Bromo-6-nitrophenol Basic information

Product Name:	2-Bromo-6-nitrophenol
Synonyms:	TIMTEC-BB SBB008567;2-Bromo-6-nitropheno;3-Bromo-2-hydroxynitrobenzene;2-BROMO-6-NITROPHENOL;6-NITRO-2-BROMOPHENOL;Phenol, 2-broMo-6-nitro-;6-BroMo-2-nitrophenol;2-BroMo-6-nitrophenol, 97+%
CAS:	13073-25-1
MF:	C6H4BrNO3
MW:	218
EINECS:	629-309-4
Product Categories:	Fluorobenzene;Aromatic Phenols;Phenol&Thiophenol&Mercaptan;Organic Building Blocks;Oxygen Compounds;Phenols
Mol File:	13073-25-1.mol

2-Bromo-6-nitrophenol Chemical Properties

Melting point	66-70 °C (lit.)
Boiling point	227.2±20.0 °C(Predicted)
density	1.881±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform; Methanol
form	Solid
pka	5.36±0.24(Predicted)
color	Yellow
CAS DataBase Reference	13073-25-1(CAS DataBase Reference)
EPA Substance Registry System	2-Bromo-6-nitrophenol (13073-25-1)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	22-36/37/38
Safety Statements	36/37-26
WGK Germany	3
Hazard Note	Harmful
HazardClass	IRRITANT
HS Code	29089990

MSDS Information

Provider	Language
SigmaAldrich	English

2-Bromo-6-nitrophenol Usage And Synthesis

Chemical Properties	White solid
Uses	2-Bromo-6-nitrophenol is an intermediate used in the synthesis of N-Hydroxy Eltrombopag (H825795), which is a derivative compound of Eltrombopag (508000), an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.

2-Bromo-6-nitrophenol Preparation Products And Raw materials

Raw materials	1-Bromo-2-nitrobenzene-->3-Bromo-2-nitrophenol-->3-Bromo-4-nitrophenol-->1-Bromo-2-methoxy-3-nitro-benzene-->2-Bromo-4-nitrophenol-->Piperidine-->2-Nitrophenol
Preparation Products	3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID-->2,4-DIBROMO-6-NITROPHENOL-->2-Bromo-3-nitrophenol-->4-Bromo-2-nitrophenol

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