4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE

4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE
  • CAS No.:84905-80-6
Other grades of this product :
4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE Basic information
Product Name:4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE
Synonyms:4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE;4-Chloro-5H-pyrrol[3,2-d] pyrimidine;5H-Pyrrolo3,2-dpyrimidine, 4-chloro-;4-chloro-5H-pyrrolo[2,3-c]pyridine;4-Chloro-5H-pyrrolo[3,2-d...;6-chloro-9-deaza-7H-purine, 4-chloro-3H,5H-pyrrolo[3,2-d]pyriMidine, 4-Chloropyrrolo<3,2-d>pyriMidine;4-chloro-1H-pyrrolo[3,2-d]pyriMidine;6-chloro-9-deaza-7H-puri
CAS:84905-80-6
MF:C6H4ClN3
MW:153.57
EINECS:632-937-1
Product Categories:Heterocycle-Pyrimidine series;CHIRAL CHEMICALS;Heterocycles series
Mol File:84905-80-6.mol
4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE Chemical Properties
Melting point 186-188 °C (decomp)(Solv: water (7732-18-5); ethanol (64-17-5))
Boiling point 325.9±22.0 °C(Predicted)
density 1.531±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka11.58±0.40(Predicted)
Safety Information
HazardClass IRRITANT
HS Code 2933599590
MSDS Information
4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE Usage And Synthesis
Description4-Chloro-5H-pyrrolo[3,2-d]pyrimidine is a purine analog that inhibits the growth of bacteria by binding to the enzyme DNA gyrase. It has been shown to be effective against staphylococcus and Mycobacterium tuberculosis.
Uses4-Chloro-5H-pyrrolo[3,2-d]pyrimidine is a chlorinated pyrrolopyrimidine used in the preparation of compounds with antibacterial and antitumor activities.
Application4-Chloro-5H-pyrrolo[3,2-d]pyrimidine binds to the enzyme DNA gyrase and prevents it from breaking down the bacterial DNA. This drug also has antimycobacterial activity due to its ability to bind to the enzyme RNA polymerase.
4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE Preparation Products And Raw materials
Preparation Products7-bromo-4-chloro-5H-pyrrolo[3,2-d]pyrimidine

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