4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE

4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE
  • CAS No.:84905-80-6

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE Basic information
Product Name:4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE
Synonyms:4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE;4-Chloro-5H-pyrrol[3,2-d] pyrimidine;5H-Pyrrolo3,2-dpyrimidine, 4-chloro-;4-chloro-5H-pyrrolo[2,3-c]pyridine;4-Chloro-5H-pyrrolo[3,2-d...;6-chloro-9-deaza-7H-purine, 4-chloro-3H,5H-pyrrolo[3,2-d]pyriMidine, 4-Chloropyrrolo<3,2-d>pyriMidine;4-chloro-1H-pyrrolo[3,2-d]pyriMidine;6-chloro-9-deaza-7H-puri
CAS:84905-80-6
MF:C6H4ClN3
MW:153.57
EINECS:632-937-1
Product Categories:Heterocycle-Pyrimidine series;CHIRAL CHEMICALS;Heterocycles series
Mol File:84905-80-6.mol
4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE Chemical Properties
Melting point 186-188 °C (decomp)(Solv: water (7732-18-5); ethanol (64-17-5))
Boiling point 325.9±22.0 °C(Predicted)
density 1.531±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka11.58±0.40(Predicted)
Safety Information
HazardClass IRRITANT
HS Code 2933599590
MSDS Information
4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE Usage And Synthesis
Description4-Chloro-5H-pyrrolo[3,2-d]pyrimidine is a purine analog that inhibits the growth of bacteria by binding to the enzyme DNA gyrase. It has been shown to be effective against staphylococcus and Mycobacterium tuberculosis.
Uses4-Chloro-5H-pyrrolo[3,2-d]pyrimidine is a chlorinated pyrrolopyrimidine used in the preparation of compounds with antibacterial and antitumor activities.
Application4-Chloro-5H-pyrrolo[3,2-d]pyrimidine binds to the enzyme DNA gyrase and prevents it from breaking down the bacterial DNA. This drug also has antimycobacterial activity due to its ability to bind to the enzyme RNA polymerase.
4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE Preparation Products And Raw materials
Preparation Products7-bromo-4-chloro-5H-pyrrolo[3,2-d]pyrimidine

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