Other grades of this product :
| tert-Butanesulfinamide Chemical Properties |
| Melting point | 97-101 °C(lit.) | | Boiling point | 220.0±23.0 °C(Predicted) | | density | 1.124 | | storage temp. | 2-8°C | | solubility | Soluble in methanol. | | pka | 10.11±0.50(Predicted) | | form | Powder or Crystals | | color | White to tan | | CAS DataBase Reference | 146374-27-8(CAS DataBase Reference) |
| WGK Germany | 3 | | HS Code | 29309090 |
| tert-Butanesulfinamide Usage And Synthesis |
| Description | (S)-tert-Butanesulfinamide (also known as 2-Methyl-2-propanesulfinamide) is used for the synthesis of 4-sulfonyliminopiperidine and its reaction with benzyl Grignard to form an important pharmaceutical building block, 4-benzyl-4-aminopiperidne.It can be also used to prepare spiro tosylaziridines via methylene insertion into the derived sulfonylimine1,2-(R)-(+)-2-Methyl-2-propanesulfinamide may be used to prepare N-(1-cyclohexylmethylidene)-2-methylpropane-2-sulfinamide via copper mediated condensation with cyclohexane carboxaldehyde. It may also be used to prepare (20E)-N-[t-butyl-(R)-sulfinyl]-3β-(t-butyldimethylsilyloxy)-pregn-5-en-20-imine, an intermediate for the development of androgen receptor antagonists. (S)-(-)-2-Methyl-2-propanesulfinamide may be used to develop benzofuran-based farnesyltransferase inhibitors as anti-cancer agents.
| | Chemical Properties | white to light yellow crystal powde | | Uses | (±)-2-Methyl-2-propanesulfinamide is used in the synthesis of 4-sulfonyliminopiperidine and its reaction with benzyl Grignard to form an important pharmaceutical building block, 4-benzyl-4-aminopiperidne. It is also used to prepare spiro tosylaziridines via methylene insertion into the derived sulfonylimine. | | Uses | Ellman′s Sulfinamides |
| tert-Butanesulfinamide Preparation Products And Raw materials |
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