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| 2-Chloropyrimidine Basic information |
| 2-Chloropyrimidine Chemical Properties |
| Melting point | 63-66 °C (lit.) | | Boiling point | 75-76 °C/10 mmHg (lit.) | | density | 1.2710 (rough estimate) | | refractive index | 1.5320 (estimate) | | Fp | 98 °C | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Methanol, Water | | pka | -1.46±0.13(Predicted) | | form | Crystals or Crystalline Powder | | color | Yellow to pale orange | | Water Solubility | Slightly soluble in water. 33.3 mg soluble in 1 mL of alcohol. | | Sensitive | Moisture Sensitive | | BRN | 107171 | | InChIKey | UNCQVRBWJWWJBF-UHFFFAOYSA-N | | CAS DataBase Reference | 1722-12-9(CAS DataBase Reference) | | NIST Chemistry Reference | Pyrimidine, 2-chloro-(1722-12-9) |
| 2-Chloropyrimidine Usage And Synthesis |
| Chemical Properties | yellowish to pale orange crystals or cryst. powder | | Uses | 2-Chloropyrimidine is a monochlorinated pyrimidine with plant growth regulating activity. Chloropyrimidine is a useful reagent in the preparation of antivirals and other biologically active compounds. | | Uses | 2-Chloropyrimidine is a useful reagent in the preparation of antivirals and other biologically active compounds. It was used in the synthesis of 4?-(1,1?-(5-(2-methoxyphenoxy)-[2,2?-bipyrimidine]-4,6-diyl)bis(1H-pyrazol-3,1-diyl)) dianiline fluorescent dye, biosensor for protein assay, 2-amino-4-heteroarylpyrimidines, cis- and trans-octahydropyrrolo[2,3]pyridine derivatives. | | General Description | 2-Chloropyrimidine undergoes cobalt-catalyzed cross-coupling reaction with aryl halides. | | Purification Methods | It has been recrystallised from *C6H6, pet ether or a mixture of both. It sublimes at 50o/18mm and can be distilled in a vacuum. [IR: Short & Thompson J Chem Soc 168 1952, Boarland & McOmie J Chem Soc 1218 1951, Beilstein 23/5 V 343.] |
| 2-Chloropyrimidine Preparation Products And Raw materials |
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