Glabridin

Glabridin
  • CAS No.:59870-68-7
Other grades of this product :
Glabridin Basic information
Product Name:Glabridin
Synonyms:1,3-Benzenediol, 4-(3,4-dihydro-8,8-diMethyl-2H,8H-benzo(1,2-b:3,4-b')dipyran-3-yl)-, (R)-;(R)-4-(3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-3-yl)-1,3-benzenediol;4-[(3R)-3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-3-yl]-1,3-benzenediol;Glabridin, >=98%;Glabridin/Propylene Glycol;4-[(3R)-8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol;Glabridin/OIL SOLUBLE LICORICE(GLYCYRRHIZA) EXTRACT;professional manufacturer Glabridin 59870-68-7
CAS:59870-68-7
MF:C20H20O4
MW:324.37
EINECS:611-908-7
Product Categories:Miscellaneous Natural Products;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Natural Plant Extract;59870-68-7
Mol File:59870-68-7.mol
Glabridin Chemical Properties
Melting point 154~155℃
Boiling point 518.6±50.0 °C(Predicted)
density 1.257±0.06 g/cm3(Predicted)
Fp 267℃
storage temp. room temp
solubility DMSO: soluble5mg/mL, clear (warmed)
form powder
pka9.66±0.40(Predicted)
color white to light brown
BRN 7141956
Stability:Hygroscopic
InChIKeyPMPYOYXFIHXBJI-ZDUSSCGKSA-N
CAS DataBase Reference59870-68-7(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29329990
MSDS Information
Glabridin Usage And Synthesis
Chemical PropertiesWhite to tan powder
UsesGlabridin is a compound extracted from Licorice (root) shows properties that are cytotoxic, antimicrobial, estrogenic and anti-proliferative.
DefinitionChEBI: A member of the class of hydroxyisoflavans that is (R)-isoflavan substituted by hydroxy groups at positions 2' and 4' and a 2,2-dimethyl-2H-pyran group across positions 7 and 8 respectively.
Biochem/physiol ActionsGlabridin is a bio-available isoflavan isolated from licorice (Glycyrrhiza glabra L.) root extract. Glabridin has been reported to posses varies biological activities including strong antioxidant activity, antioxidant against LDL oxidation, anti-Helicobacter pylori properties, estrogen-like activity and antinephritic and radical scavenging activities. Also it appears to inhibit serotonin re-uptake, melanogenesis, inflammation and cytochrome P450 3A4, 2B6, and 2C9.
Glabridin Preparation Products And Raw materials

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