2-Benzothiazolamine

2-Benzothiazolamine
  • CAS No.:136-95-8
Other grades of this product :

2-Benzothiazolamine Basic information
Product Name:2-Benzothiazolamine
Synonyms:2-Aminobenzthiazole;2-Iminobenzothiazoline;o-Aminobenzothiazole;u-Aminoben-zothiazole;USAF EK-3941;USAF xr-27;usafek-3941;usafxr-27
CAS:136-95-8
MF:C7H6N2S
MW:150.2
EINECS:205-268-4
Product Categories:Metabolites & Impurities, Miscellaneous Reagents, Sulfur & Selenium Compounds;Metabolites & Impurities;BENZOTHIAZOLE;Intermediates of Dyes and Pigments;Miscellaneous Reagents;Sulfur & Selenium Compounds;Sulphur Derivatives;Heterocyclic Compounds
Mol File:136-95-8.mol
2-Benzothiazolamine Chemical Properties
Melting point 126-129 °C (lit.)
Boiling point 190-195 °C(Press: 0.05 Torr)
density 1.2162 (rough estimate)
refractive index 1.5500 (estimate)
storage temp. Store below +30°C.
solubility Soluble in alcohol, chloroform, diethyl ether.
form Powder or Flakes
pkapK1: 4.48(+1) (20°C)
color Beige to grayish
Water Solubility <0.1 g/100 mL at 19 ºC
Merck 14,424
BRN 116315
CAS DataBase Reference136-95-8(CAS DataBase Reference)
NIST Chemistry ReferenceBenzothiazole, 2-amino-(136-95-8)
EPA Substance Registry System2-Aminobenzothiazole (136-95-8)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36
Safety Statements 26
RIDADR UN 2811 6.1/PG 3
WGK Germany 2
RTECS DL1050000
Hazard Note Irritant
TSCA Yes
HS Code 29342080
Hazardous Substances Data136-95-8(Hazardous Substances Data)
MSDS Information
ProviderLanguage
2-BenzothiazolamineEnglish
SigmaAldrichEnglish
ACROSEnglish
ALFAEnglish
2-Benzothiazolamine Usage And Synthesis
Chemical PropertiesBEIGE TO GREYISH POWDER OR FLAKES
UsesAn impurity of pramipexole production
Uses2-Aminobenzothiazole was used in the synthesis of cobalt(II) picrate mixed-ligand complexes. It was used to study adsorption of biologically significant 2-aminobenzothiazole molecules on colloidal silver particles using surface-enhanced raman scattering spectroscopy
Uses2-Aminobenzothiazole was used in the synthesis of cobalt(II) picrate mixed-ligand complexes. It was used to study adsorption of biologically significant 2-aminobenzothiazole molecules on colloidal silver particles using surface-enhanced raman scattering spectroscopy.
General DescriptionOdorless gray to white powder.
Air & Water ReactionsInsoluble in water.
Reactivity ProfileAn amine, organosulfide. Organosulfides are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. Many of these compounds may liberate hydrogen sulfide upon decomposition or reaction with an acid. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Fire HazardFlash point data for 2-Benzothiazolamine are not available; however, 2-Benzothiazolamine is probably combustible.
Biochem/physiol Actions2-Aminobenzothiazole has local anaesthetic action and has numerous applications in human and veterinary medicine.
Purification MethodsThe thiazole cystallises from a H2O, aqueous EtOH, *C6H6 or pet ether. The hydrochloride crystallises from dilute HCl and has m 240.5o. [Beilstein 27 H 182, 27 III/IV 4824.]
2-Benzothiazolamine Preparation Products And Raw materials
Raw materialsDisulfur dichloride-->1-PHENYL-2-THIOUREA
Preparation Products2-Bromo-1,3-benzothiazole-->Cationic Brilliant Blue RL-->(2S,3R)-(+)-3-Isopropyl-2-phenyl-3,4-dihydro-2H-pyrimido[2,1-b][1,3]benzothiazole98+%-->2-IODOBENZOTHIAZOLE-->2-Amino-6-nitrobenzothiazole-->2,2'-Diaminodiphenyl disulphide-->2-Chlorobenzothiazole-->3-[[4-[(Benzothiazol-2-yl)azo]-3-methylphenyl](2-hydroxyethyl)amino]propanenitrile-->C.I. Basic Red 53-->Basic Blue  53

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