2-Methyl butyric acid

2-Methyl butyric acid
  • CAS No.:116-53-0
Other grades of this product :
2-Methyl butyric acid Basic information
Description References
Product Name:2-Methyl butyric acid
Synonyms:METHYLBUTYRIC ACID, DL-2-;METHYLETHYL ACETIC ACID;(+/-)-2-METHYLBUTYRIC ACID;2-METHYLBUTYRIC ACID;2-METHYLBUTANOIC ACID;RARECHEM AL BO 0094;BUTANE-2-CARBOXYLIC ACID;FEMA 2695
CAS:116-53-0
MF:C5H10O2
MW:102.13
EINECS:204-145-2
Product Categories:Carboxylic Acids;Alphabetical Listings;Flavors and Fragrances;M-N;C1 to C5;Carbonyl Compounds;Certified Natural ProductsFlavors and Fragrances
Mol File:116-53-0.mol
2-Methyl butyric acid Chemical Properties
Melting point -70 °C
Boiling point 176-177 °C (lit.)
density 0.936 g/mL at 25 °C (lit.)
vapor pressure 0.5 mm Hg ( 20 °C)
refractive index n20/D 1.405(lit.)
FEMA 2695 | 2-METHYLBUTYRIC ACID
Fp 165 °F
storage temp. Sealed in dry,Room Temperature
solubility 20g/l
form Liquid
pka4.8(at 25℃)
color Clear colorless to pale yellow
explosive limit1.6-7.3%(V)
Water Solubility 45 g/L (20 ºC)
JECFA Number255
BRN 1720486
LogP1.8 at 25℃
CAS DataBase Reference116-53-0(CAS DataBase Reference)
NIST Chemistry ReferenceButanoic acid, 2-methyl-(116-53-0)
EPA Substance Registry System2-Methylbutyric acid (116-53-0)
Safety Information
Hazard Codes C
Risk Statements 21/22-34
Safety Statements 26-36/37/39-45
RIDADR UN 3265 8/PG 3
WGK Germany 1
RTECS EK7897000
13
TSCA Yes
HazardClass 8
PackingGroup III
HS Code 29156090
MSDS Information
ProviderLanguage
2-Methyl butyric acid English
ACROS English
SigmaAldrich English
ALFA English
2-Methyl butyric acid Usage And Synthesis
Description2-methyl butyric acid has a pungent, acrid odor which is similar to Roquefort cheese with an acrid taste. At low dilutions, it has a pleasant fruity taste. It can be prepared either by decarboxylation of methyl ethyl malonic acid or by the oxidation of fermentation amyl alcohol (fusel oil). It is used as a flavor ingredient for butter, cream, cheese flavor deployment. It also provides acyl moiety for the preparation of the respective flavor esters.
References[1] George A. Burdock, Encyclopedia of Food and Color Additives, Band 1, 1996 [2] T. Tachihara, H. Hashimoto, S. Ishizaki, T. Komai, A. Fujita, M. Ishikawa and T. Kitahara, Microbial resolution of 2-methylbutyric acid and its application to several chiral flavour compounds, Developments in Food Science, 2006, vol. 43, 97-100
Description2-Methylbutyric acid has a pungent, acrid odor similar to Roquefort cheese with an acrid taste. At low dilutions, it has a pleasant fruity taste. May be prepared by decarboxylation of methyl ethyl malonic acid (with heat); also by oxidation of fermentation amyl alcohol (fusel oil).
Chemical Properties2-Methylbutyric acid has a pungent, acrid odor similar to Roquefort cheese with an acrid taste. At low dilutions, it has a pleasant, fruity taste
Chemical Propertiesclear colorless to pale yellowish liquid
OccurrenceOccurring as the d-, l-, and dl-isomers; the racemic form has been reported found in angelica root oil and coffee; the d-isomer in the ester form has been identified in lavender oil. Also reported found in apple, apricot, berries, grapes, papaya, peach, guava, pineapple, potato, bell pepper, tomato, peppermint and spearmint oil, vinegar, wheat breads, cheeses, chicken, mutton, pork, hop oil, beer, cognac, rum, whiskies, cider, cocoa, coffee, tea, peanuts, passion fruit, trassi, mango, plum, tamarind, rice, corn oil, loquat, scallops, Chinese quince, maté, mammee apple and Roman chamomile oil, cranberry, grape brandy, oriental tobacco, and strawberry
Uses2-Methylbutyric acid, can be used as food additive for butter, cream, cheese flavor deployment. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff. It is also used in the synthesis of 2-methylbutyric anhydride.
Uses2-Methylbutyric acid was used in the synthesis of 2-methylbutyric anhydride, an acylating agent.
UsesUsed in the synthesis of 2-methylbutyric anhydride
PreparationBy decarboxylation of methyl ethyl malonic acid (with heat); also by oxidation of fermentation amyl alcohol (fusel oil).
DefinitionChEBI: A methylbutyric acid comprising a butyric acid core carrying a 2-methyl substituent. Produced from amino acid leucine during nutrient starvation in bacteria.
Aroma threshold valuesDetection: 10 to 60 ppb. Aroma characteristics at 1.0%: acidic sour, pungent, ripe fruit leather, lingonberry, dirty cheesy, fermented pineapple fruity with a woody nuance
Taste threshold valuesTaste characteristics at 10 ppm: dirty, acidic sour, ripe fruity, with a dairy buttery and cheesy nuance
General DescriptionEnantioselective esterification of (+/-)-2-methylbutynic acid catalyzed by Chromobacterium viscosum lipase immobilized in microemulsion-based organogels has been investigated.
Flammability and ExplosibilityNotclassified
Biochem/physiol ActionsTaste at 10 ppm

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